ChemSpider 2D Image | MJ15 | C23H17Cl3N4O

MJ15

  • Molecular FormulaC23H17Cl3N4O
  • Average mass471.766 Da
  • Monoisotopic mass470.046783 Da
  • ChemSpider ID24742166

More details:

Validated by Experts, Validated by Users, Non-Validated, Removed by Users

1H-Pyrazole-3-carboxamide, 5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-4-methyl-N-(3-pyridinylmethyl)- [ACD/Index Name]
5-(4-Chlorophenyl)-1-(2,4-dichlorophenyl)-4-methyl-N-(3-pyridinylmethyl)-1H-pyrazole-3-carboxamide [ACD/IUPAC Name]
5-(4-Chlorophényl)-1-(2,4-dichlorophényl)-4-méthyl-N-(3-pyridinylméthyl)-1H-pyrazole-3-carboxamide [French] [ACD/IUPAC Name]
5-(4-Chlorphenyl)-1-(2,4-dichlorphenyl)-4-methyl-N-(3-pyridinylmethyl)-1H-pyrazol-3-carboxamid [German] [ACD/IUPAC Name]
944154-76-1 [RN]
MJ 15
MJ15
MJ-15
N6MZ4N936N
[944154-76-1] [RN]
More...
  • Experimental Physico-chemical Properties
  • Miscellaneous

    • Safety:

      Sold under licence. Tocris Bioscience 4063

    • Bio Activity:

      7-TM Receptors Tocris Bioscience 4063
      Cannabinoid Receptors Tocris Bioscience 4063
      CB1 Receptors Tocris Bioscience 4063
      Potent and selective CB1 antagonist Tocris Bioscience 4063
      Potent and selective CB1 receptor antagonist (Ki = 27.2 pM, IC50 = 118.9 pM for rat CB1 receptors). Exhibits potency in obesity and hyperlipidemia models; inhibits food intake and increases in body we ight in diet-induced obese rats and mice. Tocris Bioscience 4063
      Potent and selective CB1 receptor antagonist (Ki = 27.2 pM, IC50 = 118.9 pM for rat CB1 receptors). Exhibits potency in obesity and hyperlipidemia models; inhibits food intake and increases in body weight in diet-induced obese rats and mice. Tocris Bioscience 4063

Predicted data is generated using the ACD/Labs Percepta Platform - PhysChem Module, version: 14.00

Density: 1.4±0.1 g/cm3
Boiling Point: 639.0±55.0 °C at 760 mmHg
Vapour Pressure: 0.0±1.9 mmHg at 25°C
Enthalpy of Vaporization: 94.4±3.0 kJ/mol
Flash Point: 340.2±31.5 °C
Index of Refraction: 1.668
Molar Refractivity: 125.9±0.5 cm3
#H bond acceptors: 5
#H bond donors: 1
#Freely Rotating Bonds: 5
#Rule of 5 Violations: 1
ACD/LogP: 5.89
ACD/LogD (pH 5.5): 5.43
ACD/BCF (pH 5.5): 7599.97
ACD/KOC (pH 5.5): 20031.90
ACD/LogD (pH 7.4): 5.49
ACD/BCF (pH 7.4): 8748.27
ACD/KOC (pH 7.4): 23058.58
Polar Surface Area: 60 Å2
Polarizability: 49.9±0.5 10-24cm3
Surface Tension: 50.7±7.0 dyne/cm
Molar Volume: 337.8±7.0 cm3

Click to predict properties on the Chemicalize site


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