Ponatinib

3-(2-(Imidazo[1,2-b]pyridazin-3-yl)ethynyl)-4-methyl-N-(4-((4-methylpiperazin-1-yl)methyl)-3-(trifluoromethyl)phenyl)benzamide

3-(2-{imidazo[1,2-b]pyridazin-3-yl}ethynyl)-4-methyl-N-{4-[(4-methylpiperazin-1-yl)methyl]-3-(trifluoromethyl)phenyl}benzamide

3-(Imidazo[1,2-b]pyridazin-3-ylethinyl)-4-methyl-N-{4-[(4-methyl-1-piperazinyl)methyl]-3-(trifluormethyl)phenyl}benzamid

3-(Imidazo[1,2-b]pyridazin-3-ylethynyl)-4-methyl-N-{4-[(4-methyl-1-piperazinyl)methyl]-3-(trifluoromethyl)phenyl}benzamide

3-(Imidazo[1,2-b]pyridazin-3-yléthynyl)-4-méthyl-N-{4-[(4-méthyl-1-pipérazinyl)méthyl]-3-(trifluorométhyl)phényl}benzamide

943319-70-8

Benzamide, 3-(2-imidazo[1,2-b]pyridazin-3-ylethynyl)-4-methyl-N-[4-[(4-methyl-1-piperazinyl)methyl]-3-(trifluoromethyl)phenyl]-

Iclusig

Ponatinib

[Wiki]

ponatinibum

0LI

1254473-64-7

1562993-37-6

3-(2-Imidazo[1,2-b]pyridazin-3-ylethynyl)-4-methyl-N-[4-[(4-methyl-1-piperazinyl)methyl]-3-(trifluoromethyl)phenyl]-benzamide

3-(2-Imidazo[1,2-b]pyridazin-3-ylethynyl)-4-methyl-N-[4-[(4-methyl-1-piperazinyl)methyl]-3-(trifluoromethyl)phenyl]benzamide

3-(2-imidazo[1,2-b]pyridazin-3-ylethynyl)-4-methyl-N-[4-[(4-methylpiperazin-1-yl)methyl]-3-(trifluoromethyl)phenyl]benzamide

3-(imidazo[1,2-b]pyridazin-3-ylethynyl)-4-methyl-N-(4-((4-methylpiperazin-1-yl)methyl)-3-(trifluoromethyl)phenyl)benzamide

3-(imidazo[1,2-b]pyridazin-3-ylethynyl)-4-methyl-N-{4-[(4-methylpiperazin-1-yl)methyl]-3-(trifluoromethyl)phenyl}benzamide

943319-70-8 (free base)

A0A090N8Q0_HUMAN

A0A0D1CGS9_USTMA

ABCG2_HUMAN

ABL1_HUMAN

AP 24534; AP24534; AP-24534

AP24534 Ponatinib

ap24534ponatinib

BCR_HUMAN

Benzamide, 3-(2-imidazo[1,2-b]-pyridazin-3-ylethynyl)-4-methyl-N-[4[(4-methyl-1-piperazinyl)-methyl]-3-(trifluoromethyl)-phenyl]-

Breakpoint cluster region protein

CDK8_HUMAN

CP3A4_HUMAN

CSF1R_HUMAN

CSK_HUMAN

Cyclin-dependent kinase 8

Cytochrome P450 3A4

DDR1_HUMAN

EPHA1_HUMAN

EPHA2_HUMAN

Ephrin type-A receptor 1

Ephrin type-A receptor 2

Ephrin type-A receptor 2 [596-900]

FGFR1_HUMAN

FGFR2_HUMAN

FGFR3_HUMAN

FGFR4_HUMAN

Fibroblast growth factor receptor 1

Fibroblast growth factor receptor 2

Fibroblast growth factor receptor 3

Fibroblast growth factor receptor 4

FLT3_HUMAN

FRK_HUMAN

FYN_HUMAN

Glycogen synthase kinase-3 beta

GSK3B_HUMAN

HCK_HUMAN

Iclusig®

IGF1R_HUMAN

Insulin-like growth factor 1 receptor

JAK1_HUMAN

JAK2_HUMAN

KAPCA_HUMAN

KCNH2_HUMAN

KIT_HUMAN

LCK_HUMAN

Leukocyte tyrosine kinase receptor

LRRK2_HUMAN

LTK_HUMAN

LYN_HUMAN

MFCD17215203

Mitogen-activated protein kinase 14

MK14_HUMAN

NTRK1_HUMAN

PGFRA_HUMAN

PGFRA_MOUSE

Ponatinb

ponatinib (ap 24534)

Ponatinib D8

ponatinib(ap 24534)

ponatinib(ap24534)

Ponatinib, Free Base

Ponatinib-d8

ponatinibum

RET_HUMAN

RIPK1_HUMAN

RIPK3_HUMAN

SRC_CHICK

SRC_HUMAN

Tyrosine-protein kinase ABL1

Tyrosine-protein kinase ABL1 [229-512]

Tyrosine-protein kinase ABL1 [T315I]

Tyrosine-protein kinase CSK

Tyrosine-protein kinase FRK

Tyrosine-protein kinase Fyn

Tyrosine-protein kinase HCK

Tyrosine-protein kinase JAK1

Tyrosine-protein kinase JAK2

Tyrosine-protein kinase Lck

Tyrosine-protein kinase Lyn

Tyrosine-protein kinase Yes

VGFR1_HUMAN

VGFR2_HUMAN

YES_HUMAN

понатиниб

بوناتينيب

泊那替尼