Found 26 results

Search term: MF = 'C_{29}H_{34}N_{6}O_{4}S_{2}'
ChemSpider 2D Image | Masitinib mesylate | C29H34N6O4S2

Masitinib mesylate

  • Molecular FormulaC29H34N6O4S2
  • Average mass594.748 Da
  • Monoisotopic mass594.208313 Da
  • ChemSpider ID29342313

More details:

Validated by Experts, Validated by Users, Non-Validated, Removed by Users

1048007-93-7 [RN]
4-[(4-Methyl-1-piperazinyl)methyl]-N-(4-methyl-3-{[4-(3-pyridinyl)-1,3-thiazol-2-yl]amino}phenyl)benzamide methanesulfonate (1:1) [ACD/IUPAC Name]
Acide méthanesulfonique - 4-[(4-méthyl-1-pipérazinyl)méthyl]-N-(4-méthyl-3-{[4-(3-pyridinyl)-1,3-thiazol-2-yl]amino}phényl)benzamide (1:1) [French] [ACD/IUPAC Name]
Benzamide, 4-[(4-methyl-1-piperazinyl)methyl]-N-[4-methyl-3-[[4-(3-pyridinyl)-2-thiazolyl]amino]phenyl]-, methanesulfonate (1:1) [ACD/Index Name]
Masitinib mesylate
Methansulfonsäure --4-[(4-methyl-1-piperazinyl)methyl]-N-(4-methyl-3-{[4-(3-pyridinyl)-1,3-thiazol-2-yl]amino}phenyl)benzamid (1:1) [German] [ACD/IUPAC Name]
N-(4-methyl-3-{[4-(pyridin-3-yl)-1,3-thiazol-2-yl]amino}phenyl)-4-[(4-methylpiperazin-1-yl)methyl]benzamide; methanesulfonic acid
[1048007-93-7] [RN]
1-(1H-Indazol-5-yl)thiourea [ACD/IUPAC Name]
4-(4-Methyl-piperazin-1-ylmethyl)-N-[4-methyl-3-(4-pyridin-3-yl-thiazol-2-ylamino)-phenyl]-benzamide methanesulfonate
More...

Validated by Experts, Validated by Users, Non-Validated, Removed by Users

ZK89EG3A18 [DBID]
UNII:ZK89EG3A18 [DBID]
UNII-ZK89EG3A18 [DBID]
  • Experimental Physico-chemical Properties
  • Miscellaneous

    • Bio Activity:

      c-Kit MedChem Express HY-10209A
      c-Kit PDGFR MedChem Express HY-10209A
      Masitinib(AB-1010) mesylate is a novel inhibitor for Kit and PDGFR?/? with IC50 of 200 nM and 540 nM/800 nM, weak inhibition to ABL and c-Fms.; IC50 value: 200 nM (Kit); 540 nM/800 nM(PDGFR?/?) [1]; Target: c-Kit; PDGFR?/?; in vitro: In Ba/F3 cells expressing human wild-type Kit, Masitinib inhibits SCF (stem cell factor)-induced cell proliferation with an IC50 of 150 nM, while the IC50 for inhibition of IL-3-stimulated proliferation is at approximately >10 ?M. MedChem Express HY-10209A
      Protein Tyrosine Kinase/RTK MedChem Express HY-10209A
      Protein Tyrosine Kinase/RTK; MedChem Express HY-10209A

Predicted data is generated using the ACD/Labs Percepta Platform - PhysChem Module, version: 14.00

No predicted properties have been calculated for this compound.

Click to predict properties on the Chemicalize site


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