ChemSpider 2D Image | (2E)-N-[4-(1-Benzoyl-4-piperidinyl)butyl]-3-(3-pyridinyl)acrylamide hydrochloride (1:1) | C24H30ClN3O2

(2E)-N-[4-(1-Benzoyl-4-piperidinyl)butyl]-3-(3-pyridinyl)acrylamide hydrochloride (1:1)

  • Molecular FormulaC24H30ClN3O2
  • Average mass427.967 Da
  • Monoisotopic mass427.202667 Da
  • ChemSpider ID29342321

  • Double-bond stereo - Double-bond stereo

More details:

Validated by Experts, Validated by Users, Non-Validated, Removed by Users

(2E)-N-[4-(1-Benzoyl-4-piperidinyl)butyl]-3-(3-pyridinyl)acrylamide hydrochloride (1:1) [ACD/IUPAC Name]
(2E)-N-[4-(1-Benzoyl-4-pipéridinyl)butyl]-3-(3-pyridinyl)acrylamide, chlorhydrate (1:1) [French] [ACD/IUPAC Name]
(2E)-N-[4-(1-Benzoyl-4-piperidinyl)butyl]-3-(3-pyridinyl)acrylamidhydrochlorid (1:1) [German] [ACD/IUPAC Name]
2-Propenamide, N-[4-(1-benzoyl-4-piperidinyl)butyl]-3-(3-pyridinyl)-, (2E)-, hydrochloride (1:1) [ACD/Index Name]
(E)-N-[4-(1-Benzoyl-piperidin-4-yl)-butyl]-3-pyridin-3-yl-acrylamide hydrochloride
1785666-54-7 [RN]
1785666-54-7 (HCl)
2727965-45-7 [RN]
2-Propenamide, N-[4-(1-benzoyl-4-piperidinyl)butyl]-3-(3-pyridinyl)-, (2E)- hydrochloride
658084-64-1 [RN]
More...

Validated by Experts, Validated by Users, Non-Validated, Removed by Users

CCRIS 4693 [DBID]
  • Experimental Physico-chemical Properties
  • Miscellaneous

    • Bio Activity:

      Enzymes Tocris Bioscience 4808
      NAMPT Tocris Bioscience 4808
      Non-competitive and potent inhibitor of NAMPT (nicotinamide phosphoribosyltransferase, visfatin, PBEF1) (Ki = 0.3 nM); inhibits NAD biosynthesis. Induces delayed cell death by apoptosis in HepG2 human liver carcinoma cells (IC50 ~1 nM). Induces apoptosis in four different neuroblastoma cell lines; also induces autophagy in SH-SY5Y cells. Potentiates the cytotoxic effects induced by etoposide (Cat. No. 1226) and cisplatin (Cat. No. 2251). Tocris Bioscience 4808
      Non-competitive and potent inhibitor of NAMPT (nicotinamide phosphoribosyltransferase, visfatin, PBEF1) (Ki = 0.3 nM); inhibits NAD biosynthesis. Induces delayed cell death by apoptosis in HepG2 human liver carcinoma cells (IC50 ~1 nM). Induces apoptosis in four different neuroblastoma cell lines; also induces autophagy in SH-SY5Y cells. Potentiates the cytotoxic effects induced by etoposide (Cat. No. 1226) and cisplatin (Cat. No. 2251). Tocris Bioscience 4808
      Non-competitive and potent NAMPT inhibitor; induces apoptosis and autophagy Tocris Bioscience 4808
      Transferases Tocris Bioscience 4808

Predicted data is generated using the ACD/Labs Percepta Platform - PhysChem Module, version: 14.00

No predicted properties have been calculated for this compound.

Click to predict properties on the Chemicalize site


Advertisement