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lorlatinib

Molecular formula:C21H19FN6O2
Average mass:406.421
Monoisotopic mass:406.155352
ChemSpider ID:32813339
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1 of 1 defined stereocentres

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Verified

(10R)-7-amino-12-fluoro-10,15,16,17-tetrahydro-2,10,16-trimethyl-15-oxo-2H-4,8-methenopyrazolo[4,3-h][2,5,11]benzoxadiazacyclotetradecine-3-carbonitrile

(10R)-7-amino-12-fluoro-2,10,16-trimethyl-15-oxo-10,15,16,17-tetrahydro-2H-4,8- methenopyrazolo[4,3-h][2,5,11]benzoxadiazacyclotetradecine-3-carbonitrile

(10R)-7-Amino-12-fluoro-2,10,16-trimethyl-15-oxo-10,15,16,17-tetrahydro-2H.8,4-(metheno)pyrazolo[4,3.h][2,5,11]-benzoxadiazacyclotetradecine-3-carbonitrile

(16R)-19-Amino-13-fluor-4,8,16-trimethyl-9-oxo-17-oxa-4,5,8,20-tetraazatetracyclo[16.3.1.0~2,6~.0~10,15~]docosa-1(22),2,5,10,12,14,18,20-octaen-3-carbonitril

[German]

 [ACD/IUPAC Name]

(16R)-19-Amino-13-fluoro-4,8,16-trimethyl-9-oxo-17-oxa-4,5,8,20-tetraazatetracyclo[16.3.1.0~2,6~.0~10,15~]docosa-1(22),2,5,10,12,14,18,20-octaene-3-carbonitrile

[ACD/IUPAC Name]

(16R)-19-Amino-13-fluoro-4,8,16-triméthyl-9-oxo-17-oxa-4,5,8,20-tétraazatétracyclo[16.3.1.0~2,6~.0~10,15~]docosa-1(22),2,5,10,12,14,18,20-octaène-3-carbonitrile

[French]

 [ACD/IUPAC Name]

1454846-35-5

[RN]

2H-8,4-Methenopyrazolo[4,3-h][2,5,11]benzoxadiazacyclotetradecine-3-carbonitrile, 7-amino-12-fluoro-10,15,16,17-tetrahydro-2,10,16-trimethyl-15-oxo-, (10R)-

[ACD/Index Name]

lorlatinib

[Wiki] link-icon [INN] [USAN]

lorlatinib

[French]

 [INN]

lorlatinib

[Spanish]

 [INN]

lorlatinibum

[Latin]

 [INN]

MFCD28144520

[MDL number]

OSP71S83EU

[UNII]

лорлатиниб

[Russian]

 [INN]

لورلاتينيب

[Arabic]

 [INN]

洛拉替尼

[Chinese]

 [INN]
Unverified

(10R)-7-amino-12-fluoro-2,10,16-trimethyl-15-oxo-10,15,16,17-tetrahydro-2H-4,8-methenopyrazolo[4,3-h][2,5,11]benzoxadiazacyclotetradecine-3-carbonitrile

(10R)-7-Amino-12-fluoro-2,10,16-trimethyl-15-oxo-10,15,16,17-tetrahydro-2H-8,4-(metheno)pyrazolo[4,3-H][2,5,11]-benzoxadiazacyclotetradecine-3-carbonitrile

(10R)-7-amino-12-fluoro-2,10,16-trimethyl-15-oxo-10,15,16,17-tetrahydro-2H-8,4-(metheno)pyrazolo[4,3-h][2,5,11]benzoxadiazacyclotetradecine-3-carbonitrile

1454846-35-5 (free base)

1924207-18-0; 1454846-35-5 (free base)

2H-4,8-Methenopyrazolo[4,3-h][2,5,11]benzoxadiazacyclotetradecine-3-carbonitrile, 7-amino-12-fluoro-10,15,16,17-tetrahydro-2,10,16-trimethyl-15-oxo-, (10R)-

ALK tyrosine kinase receptor

ALK tyrosine kinase receptor [L1196M]

ALK_HUMAN

HG2A_HUMAN

loratinib

Lorbrena

lorlantinib

Lorlatinib (PF-06463922)

lorlatinib; lorlatinibum

lorlatinibum

PFE-PKIS 10

ROS1_HUMAN

лорлатиниб

لورلاتينيب

洛拉替尼

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