Found 3412 results

Search term: MF = 'C_{14}H_{15}N_{3}O_{4}S'
ChemSpider 2D Image | PF-1355 | C14H15N3O4S

PF-1355

  • Molecular FormulaC14H15N3O4S
  • Average mass321.352 Da
  • Monoisotopic mass321.078339 Da
  • ChemSpider ID58830971

More details:

Validated by Experts, Validated by Users, Non-Validated, Removed by Users

1(2H)-Pyrimidineacetamide, 6-(2,5-dimethoxyphenyl)-3,4-dihydro-4-oxo-2-thioxo- [ACD/Index Name]
1435467-38-1 [RN]
2-[6-(2,5-Dimethoxyphenyl)-4-oxo-2-thioxo-3,4-dihydro-1(2H)-pyrimidinyl]acetamid [German] [ACD/IUPAC Name]
2-[6-(2,5-Dimethoxyphenyl)-4-oxo-2-thioxo-3,4-dihydro-1(2H)-pyrimidinyl]acetamide [ACD/IUPAC Name]
2-[6-(2,5-Diméthoxyphényl)-4-oxo-2-thioxo-3,4-dihydro-1(2H)-pyrimidinyl]acétamide [French] [ACD/IUPAC Name]
6-(2,5-dimethoxyphenyl)-3,4-dihydro-4-oxo-2-thioxo-1(2H)-pyrimidineacetamide
PF-1355
[1435467-38-1] [RN]
2-(6-(2,5-Dimethoxyphenyl)-4-oxo-2-thioxo-3,4-dihydropyrimidin-1(2H)-yl)acetamide
2-[6-(2,5-dimethoxyphenyl)-4-oxo-2-sulfanylidene-1,2,3,4-tetrahydropyrimidin-1-yl]acetamide
More...
  • Experimental Physico-chemical Properties
  • Miscellaneous

    • Safety:

      Sold for research purposes under agreement from Pfizer Inc Tocris Bioscience 6004

    • Bio Activity:

      Enzymes Tocris Bioscience 6004
      Other Oxygenases/Oxidases Tocris Bioscience 6004
      Oxygenases/Oxidases Tocris Bioscience 6004
      Selective myeloperoxidase (MPO) inhibitor Tocris Bioscience 6004
      Selective myeloperoxidase (MPO) inhibitor (IC50 = 1.5 ?M in LPS-stimulated human whole blood). Selective for MPO over a panel of 50 receptors, enzymes, ion channels and transporters, including thyroid peroxidase. Inhibits MPO activity in peritoneal lavage and plasma in a murine peritonitis model. Also reduces lung edema in a murine pulmonary immune complex vasculitis model. Orally bioavailable. Tocris Bioscience 6004
      Selective myeloperoxidase (MPO) inhibitor (IC50 = 1.5 muM in LPS-stimulated human whole blood). Selective for MPO over a panel of 50 receptors, enzymes, ion channels and transporters, including thyroid peroxidase. Inhibits MPO activity in peritoneal lavage and plasma in a murine peritonitis model. Also reduces lung edema in a murine pulmonary immune complex vasculitis model. Orally bioavailable. Tocris Bioscience 6004

Predicted data is generated using the ACD/Labs Percepta Platform - PhysChem Module, version: 14.00

Density: 1.4±0.1 g/cm3
Boiling Point:
Vapour Pressure:
Enthalpy of Vaporization:
Flash Point:
Index of Refraction: 1.666
Molar Refractivity: 83.4±0.4 cm3
#H bond acceptors: 7
#H bond donors: 3
#Freely Rotating Bonds: 5
#Rule of 5 Violations: 0
ACD/LogP: 0.64
ACD/LogD (pH 5.5): 0.30
ACD/BCF (pH 5.5): 1.00
ACD/KOC (pH 5.5): 33.94
ACD/LogD (pH 7.4): -0.35
ACD/BCF (pH 7.4): 1.00
ACD/KOC (pH 7.4): 7.61
Polar Surface Area: 126 Å2
Polarizability: 33.1±0.5 10-24cm3
Surface Tension: 73.7±5.0 dyne/cm
Molar Volume: 224.2±5.0 cm3

Click to predict properties on the Chemicalize site


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