Afatinib

(2E)-N-(4-[(3-chloro-4-fluorophenyl)amino]-7-{[(3S)-tetrahydrofuran-3-yl]oxy}quinazolin-6-yl)-4-(dimethylamino)but-2-enamide

(2E)-N-[4-(3-chloro-4-fluoroanilino]-7-{[(3S)-oxolan- 3-yl]oxy}quinazolin-6-y]-4-(diméthylamino)but-2-énamide

(2E)-N-[4-(3-cloro-4-fluoroanilino)-7-{[(3S)-oxolan- 3-il]oxi}quinazolin-6-il]-4-(dimetilamino)but-2-enamida

(2E)-N-{4-[(3-Chlor-4-fluorphenyl)amino]-7-[(3S)-tetrahydro-3-furanyloxy]-6-chinazolinyl}-4-(dimethylamino)-2-butenamid

(2E)-N-{4-[(3-chloro-4-fluorophenyl)amino]-7-[(3S)-oxolan-3-yloxy]quinazolin-6-yl}-4-(dimethylamino)but-2-enamide

(2E)-N-{4-[(3-Chloro-4-fluorophenyl)amino]-7-[(3S)-tetrahydro-3-furanyloxy]-6-quinazolinyl}-4-(dimethylamino)-2-butenamide

(2E)-N-{4-[(3-Chloro-4-fluorophényl)amino]-7-[(3S)-tétrahydro-3-furanyloxy]-6-quinazolinyl}-4-(diméthylamino)-2-buténamide

2-Butenamide, N-[4-[(3-chloro-4-fluorophenyl)amino]-7-[[(3S)-tetrahydro-3-furanyl]oxy]-6-quinazolinyl]-4-(dimethylamino)-, (2E)-

439081-18-2

850140-72-6

Afatinib

[Wiki]

afatinibum

Gilotrif

N-[4-(3-chloro-4-fluoroanilino)-7-[[(3S)-3-oxolanyl]oxy]-6-quinazolinyl]-4-(dimethylamino)-2-butenamide

Tomtovok

Tovok

(2E)-4-[(3-chloro-4-fluorophenyl)amino]-6-{[4-(N,N-dimethylamino)-1-oxo-2-buten-1-yl]amino}-7-((S)-tetrahydrofuran-3-yloxy)-quinazoline

(2E)-N-(4-((3-chloro-4-fluorophenyl)amino)-7-(((3S)-tetrahydro-3-furanyl)oxy)-6-quinazolinyl)-4-(dimethylamino)-2-butenamide

(2E)-N-[4-[(3-Chloro-4-fluorophenyl)amino]-7-[[(3S)-tetrahydro-3-furanyl]oxy]-6-quinazolinyl]-4-(dimethylamino)-2-butenamide

(2E)-N-{4-[(3-chloro-4-fluorophenyl)amino]-7-[(3S)-tetrahydrofuran-3-yloxy]quinazolin-6-yl}-4-(dimethylamino)but-2-enamide

(e)-n-[4-(3-chloro-4-fluoro-anilino)-7-[(3s)-tetrahydrofuran-3-yl]oxy-quinazolin-6-yl]-4-(dimethylamino)but-2-enamide

(E)-N-[4-(3-chloro-4-fluoroanilino)-7-[(3S)-oxolan-3-yl]oxyquinazolin-6-yl]-4-(dimethylamino)but-2-enamide

(E)-N-[4-(3-chloro-4-fluoroanilino)-7-[[(3S)-3-oxolanyl]oxy]-6-quinazolinyl]-4-(dimethylamino)-2-butenamide

(E/Z)-Afatinib

(R,E)-N-(4-(3-chloro-4-fluorophenylamino)-7-(tetrahydrofuran-3-yloxy)quinazolin-6-yl)-4-(dimethylamino)but-2-enamide

(S)-N-(4-((3-chloro -4-fluorophenyl)amino)-7-((tetrahydrofuran-3-yl)oxy)quinazolin-6-yl)-4-(dimethylamino)but-2-enamide

(S)-N-(4-((3-CHLORO-4-FLUOROPHENYL)AMINO)-7-((TETRAHYDROFURAN-3-YL)OXY)QUINAZOLIN-6-YL)-4-(DIMETHYLAMINO)BUT-2-ENAMIDE

(S,E)-N-(4-((3-Chloro-4-fluorophenyl)amino)-7-((tetrahydrofuran-3-yl)oxy)quinazolin-6-yl)-4-(dimethylamino)but-2-enamide

(S,E)-N-(4-(3-chloro-4-fluorophenylamino)-7-(tetrahydrofuran-3-yloxy)quinazolin-6-yl)-4-(dimethylamino)but-2-enamide

0WM

1313874-96-2

1680184-59-1

2-Butenamide, N-[4-[(3-chloro-4-fluorophenyl)amino]-7-[[(3S)-tetrahydro-3-furanyl]oxy]-6-quinazolinyl]-4-(dimethylamino)-

2-Butenamide, N-[4-[(3-chloro-4-fluorophenyl)amino]-7-[[(3S)-tetrahydro-3-furanyl]oxy]-6-quinazolinyl]-4-(dimethylamino)-, (2Z)-

439081-18-2 (free base)

441019-91-6

850140-72-6 (free base)

95%

ABL1_HUMAN

afatinib (bibw 2992)

Afatinib D6

Afatinib E-Isomer

Afatinib free base

AFATINIB N-OXIDE

afatinib(bibw 2992)

AFATINIB-D4

Afatinib-d6

afatinib/bibw2992

Afatinib; BIBW2992

afatinibum

BIBW-2992;BIBW2992;BIBW 2992

BIBW2992 (Tovok)

CATC_HUMAN

Dipeptidyl peptidase 1

EGFR_HUMAN

EPHA2_HUMAN

Ephrin type-A receptor 2

Epidermal growth factor receptor

ERBB2_HUMAN

ERBB4_HUMAN

FGFR1_HUMAN

Fibroblast growth factor receptor 1

Gilotrif®

IGF1R_HUMAN

Insulin-like growth factor 1 receptor

KCNH2_HUMAN

KIT_HUMAN

MFCD12407405

MFCD31630115

N-4-(3-chloro-4 -fluorophenyl)amino-7-(3S)-tetrahydro-3-furanyloxy-6-quinazolinyl-4-(dimethylamino)-2-butenamide

N-4-(3-chloro-4-fluorophenyl)amino-7-(3S)-tetrahydro-3-furanyloxy-6-quinazolinyl-4-(dimethyl 2-butenamide

N-4-(3-chloro-4-fluorophenyl)amino-7-(3S)-tetrahydro-3-furanyloxy-6-quinazolinyl-4-(dimethylamino)-2-butenamide

N-[4-[(3-chloro-4-fluorophenyl)amino]-7-[[(3S)-tetrahydro-3-furanyl]oxy]-6-quinazolinyl]-4-(dimethylamino)-2-Butenamide

N-[4-[(3-Chloro-4-fluorophenyl)amino]-7-[[(3″S″)-tetrahydro-3-furanyl]oxy]-6-quinazolinyl]-4(dimethylamino)-2-butenamide

N-{4-[(3-chloro-4-fluorophenyl)amino]-7-[(3S)-oxolan-3-yloxy]quinazolin-6-yl}-4-(dimethylamino)but-2-enamide

PGFRA_HUMAN

PGFRB_HUMAN

Receptor tyrosine-protein kinase erbB-2

Receptor tyrosine-protein kinase erbB-4

RET_HUMAN

SRC_HUMAN

Tyrosine-protein kinase ABL1

VGFR1_HUMAN

VGFR2_HUMAN

阿法替尼