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Put a ring on it: application of small aliphatic rings in medicinal chemistry . Matthias R. Bauer, Paolo Di Fruscia, Simon C. C. Lucas, Iacovos N. Michaelides, Jennifer E. Nelson, R. Ian Storer, Benjamin C. Whitehurst
, RSC Med. Chem.
, 2021
, 12
, 448
Reductive aminations by imine reductases: from milligrams to tons . Amelia K. Gilio, Thomas W. Thorpe, Nicholas Turner, Gideon Grogan
, Chem. Sci.
, 2022
, 13
, 4697
Dual inhibitors of LSD1 and spermine oxidase . Steven Holshouser, Matthew Dunworth, Tracy Murray-Stewart, Yuri K. Peterson, Pieter Burger, Joy Kirkpatrick, Huan-Huan Chen, Robert A. Casero, Patrick M. Woster
, Med. Chem. Commun.
, 2019
, 10
, 778
Biocatalytic reductive aminations with NAD(P)H-dependent enzymes: enzyme discovery, engineering and synthetic applications . Bo Yuan, Dameng Yang, Ge Qu, Nicholas J. Turner, Zhoutong Sun
, Chem. Soc. Rev.
, 2024
, 53
, 227
3D-QSAR, molecular docking, and molecular dynamics simulation study of thieno[3,2-b ]pyrrole-5-carboxamide derivatives as LSD1 inhibitors . Yongtao Xu, Zihao He, Hongyi Liu, Yifan Chen, Yunlong Gao, Songjie Zhang, Meiting Wang, Xiaoyuan Lu, Chang Wang, Zongya Zhao, Yan Liu, Junqiang Zhao, Yi Yu, Min Yang
, RSC Adv.
, 2020
, 10
, 6927
Novel spirocyclic tranylcypromine derivatives as lysine-specific demethylase 1 (LSD1) inhibitors . Ying Shi, Yan-Ran Wu, Ming-Bo Su, Dong-Hao Shen, Hendra Gunosewoyo, Fan Yang, Jia Li, Jie Tang, Yu-Bo Zhou, Li-Fang Yu
, RSC Adv.
, 2018
, 8
, 1666
Improvement of (S )-selective imine reductase GF3546 for the synthesis of chiral cyclic amines . Yuta Fukawa, Keita Yoshida, Sayaka Degura, Koichi Mitsukura, Toyokazu Yoshida
, Chem. Commun.
, 2022
, 58
, 13222
Chemoenzymatic total synthesis of rotigotine via IRED-catalyzed reductive amination . Dongyu Tang, Yaqing Ma, Jinping Bao, Shushan Gao, Shuli Man, Chengsen Cui
, Org. Biomol. Chem.
, 2024
, 22
, 3843
Semi-rational design of an imine reductase for asymmetric synthesis of alkylated S -4-azepanamines . Fangfang Zhu, Jun Zhang, Yaqing Ma, Lujia Yang, Qiang Gao, Shushan Gao, Chengsen Cui
, Org. Biomol. Chem.
, 2023
, 21
, 4181
Photocatalytic intermolecular bromonitroalkylation of styrenes: synthesis of cyclopropylamine derivatives and their evaluation as LSD1 inhibitors . Darong Kim, Hui-Jeon Jeon, Yoonna Kwak, Sun Joo Lee, Tae-Gyu Nam, Ji Hoon Yu, Hongchan An, Ki Bum Hong
, RSC Adv.
, 2024
, 14
, 831