ChemSpider 2D Image | UCL 2077 | C25H22N2

UCL 2077

  • Molecular FormulaC25H22N2
  • Average mass350.456 Da
  • Monoisotopic mass350.178314 Da
  • ChemSpider ID21475141

More details:

Validated by Experts, Validated by Users, Non-Validated, Removed by Users

(3-Triphenylmethylaminomethyl)pyridine
1,1,1-Triphenyl-N-(3-pyridinylmethyl)methanamin [German] [ACD/IUPAC Name]
1,1,1-Triphenyl-N-(3-pyridinylmethyl)methanamine [ACD/IUPAC Name]
1,1,1-Triphényl-N-(3-pyridinylméthyl)méthanamine [French] [ACD/IUPAC Name]
1,1,1-Triphenyl-N-(pyridin-3-ylmethyl)methanamine
3-Pyridinemethanamine, N-(triphenylmethyl)- [ACD/Index Name]
918311-87-2 [RN]
MFCD00585879
UCL 2077
(3-TRIBENZYLAMINOMETHYL)PYRIDINE
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Validated by Experts, Validated by Users, Non-Validated, Removed by Users

ML250 | [DBID]
  • Experimental Physico-chemical Properties
  • Miscellaneous

    • Bio Activity:

      Ca2+-Activated Potassium Channels Tocris Bioscience 2661
      Ion Channels Tocris Bioscience 2661
      Potassium Channels Tocris Bioscience 2661
      Slow afterhyperpolarization (sAHP) channel blocker; reduces sAHP in hippocampal slice preparations. Displays no effect on Ca2+ currents or the time course of sAHP/sIAHP. Exhibits potent inhibition of KCNQ1 and KCNQ2, but differential effects at other KCNQs. Rescues memory retrieval in dopamine ?-hydroxylase knockout mice. Tocris Bioscience 2661
      Slow afterhyperpolarization (sAHP) channel blocker; reduces sAHP in hippocampal slice preparations. Displays no effect on Ca2+ currents or the time course of sAHP/sIAHP. Exhibits potent inhibition of KCNQ1 and KCNQ2, but differential effects at other KCNQs. Rescues memory retrieval in dopamine ?-hydroxylase knockout mice. Tocris Bioscience 2661
      Slow afterhyperpolarization (sAHP) channel blocker; reduces sAHP in hippocampal slice preparations. Displays no effect on Ca2+ currents or the time course of sAHP/sIAHP. Exhibits potent inhibition of KCNQ1 and KCNQ2, but differential effects at other KCNQs. Rescues memory retrieval in dopamine beta-hydroxylase knockout mice. Tocris Bioscience 2661
      Slow afterhyperpolarization (sAHP) channel blocker; sub-type selective Kv channel effects Tocris Bioscience 2661

Predicted data is generated using the ACD/Labs Percepta Platform - PhysChem Module, version: 14.00

Density: 1.1±0.1 g/cm3
Boiling Point: 498.0±40.0 °C at 760 mmHg
Vapour Pressure: 0.0±1.3 mmHg at 25°C
Enthalpy of Vaporization: 76.6±3.0 kJ/mol
Flash Point: 255.0±27.3 °C
Index of Refraction: 1.625
Molar Refractivity: 110.3±0.3 cm3
#H bond acceptors: 2
#H bond donors: 1
#Freely Rotating Bonds: 6
#Rule of 5 Violations: 1
ACD/LogP: 5.78
ACD/LogD (pH 5.5): 5.20
ACD/BCF (pH 5.5): 4004.16
ACD/KOC (pH 5.5): 9580.47
ACD/LogD (pH 7.4): 5.68
ACD/BCF (pH 7.4): 12023.32
ACD/KOC (pH 7.4): 28767.33
Polar Surface Area: 25 Å2
Polarizability: 43.7±0.5 10-24cm3
Surface Tension: 47.3±3.0 dyne/cm
Molar Volume: 312.0±3.0 cm3

Click to predict properties on the Chemicalize site


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