ChemSpider 2D Image | 5-Chloro-3-ethyl-N-{2-[4-(piperidin-1-yl)phenyl]ethyl}-1H-indole-2-carboxamide | C24H28ClN3O

5-Chloro-3-ethyl-N-{2-[4-(piperidin-1-yl)phenyl]ethyl}-1H-indole-2-carboxamide

  • Molecular FormulaC24H28ClN3O
  • Average mass409.952 Da
  • Monoisotopic mass409.192078 Da
  • ChemSpider ID22369629

More details:

Validated by Experts, Validated by Users, Non-Validated, Removed by Users

5-Chloro-3-ethyl-N-{2-[4-(piperidin-1-yl)phenyl]ethyl}-1H-indole-2-carboxamide
1H-Indole-2-carboxamide, 5-chloro-3-ethyl-N-[2-[4-(1-piperidinyl)phenyl]ethyl]- [ACD/Index Name]
278-169-7 [EINECS]
5-Chlor-3-ethyl-N-{2-[4-(1-piperidinyl)phenyl]ethyl}-1H-indol-2-carboxamid [German] [ACD/IUPAC Name]
5-Chloro-3-ethyl-1H-indole-2-carboxylic acid [2-(4-piperidin-1-ylphenyl)ethyl]amide
5-Chloro-3-ethyl-N-[2-[4-(1-piperidinyl)phenyl]ethyl]-1H-indole-2-carboxamide
5-Chloro-3-ethyl-N-{2-[4-(1-piperidinyl)phenyl]ethyl}-1H-indole-2-carboxamide [ACD/IUPAC Name]
5-Chloro-3-éthyl-N-{2-[4-(1-pipéridinyl)phényl]éthyl}-1H-indole-2-carboxamide [French] [ACD/IUPAC Name]
868273-06-7 [RN]
MFCD11045300
More...
  • Experimental Physico-chemical Properties
  • Miscellaneous

    • Target Organs:

      Cannabinoid Receptor modulator TargetMol T2635

    • Bio Activity:

      7-TM Receptors Tocris Bioscience 2957
      Cannabinoid Receptor MedChem Express HY-13288
      Cannabinoid Receptors Tocris Bioscience 2957
      CB1 receptor TargetMol T2635
      CB1 Receptors Tocris Bioscience 2957
      GPCR/G protein MedChem Express HY-13288
      GPCR/G Protein TargetMol T2635
      GPCR/G protein; MedChem Express HY-13288
      Org 27569 is an allosteric modulator of cannabinoid CB1 receptor, induces a CB1 receptor state that is characterized by enhanced agonist affinity and decreased inverse agonist affinity. MedChem Express
      Org 27569 is an allosteric modulator of cannabinoid CB1 receptor, induces a CB1 receptor state that is characterized by enhanced agonist affinity and decreased inverse agonist affinity.; IC50 value:; Target: CB1 receptor; Org 27569 is a potent CB1 receptor allosteric modulator (pEC50 = 8.24). MedChem Express HY-13288
      Org 27569 is an allosteric modulator of cannabinoid CB1 receptor, induces a CB1 receptor state that is characterized by enhanced agonist affinity and decreased inverse agonist affinity.;IC50 value:;Target: CB1 receptorOrg 27569 is a potent CB1 receptor allosteric modulator (pEC50 = 8.24). Org 27569 significantly increases binding of the CB1 agonist [3H]CP 55.940 (pKb = 5.67) and decreases binding of the CB1 inverse agonist [3H]SR 141716A (pKb = 5.95). Org 27569 inhibits CB1 receptor antagonist efficacy in vitro (pKb = 7.57). MedChem Express HY-13288
      Potent allosteric CB1 modulator Tocris Bioscience 2957
      Potent CB1 receptor allosteric modulator (pEC50 = 8.24). Significantly increases binding of the CB1 agonist [3H]CP 55.940 (pKb = 5.67) and decreases binding of the CB1 inverse agonist [3H]SR 141716A ( pKb = 5.95). Inhibits CB1 receptor antagonist efficacy in vitro (pKb = 7.57). Tocris Bioscience 2957
      Potent CB1 receptor allosteric modulator (pEC50 = 8.24). Significantly increases binding of the CB1 agonist [3H]CP 55.940 (pKb = 5.67) and decreases binding of the CB1 inverse agonist [3H]SR 141716A (pKb = 5.95). Inhibits CB1 receptor antagonist efficacy in vitro (pKb = 7.57). Tocris Bioscience 2957

Predicted data is generated using the ACD/Labs Percepta Platform - PhysChem Module, version: 14.00

Density: 1.2±0.1 g/cm3
Boiling Point: 660.3±55.0 °C at 760 mmHg
Vapour Pressure: 0.0±2.0 mmHg at 25°C
Enthalpy of Vaporization: 97.2±3.0 kJ/mol
Flash Point: 353.2±31.5 °C
Index of Refraction: 1.635
Molar Refractivity: 120.5±0.3 cm3
#H bond acceptors: 4
#H bond donors: 2
#Freely Rotating Bonds: 6
#Rule of 5 Violations: 1
ACD/LogP: 6.36
ACD/LogD (pH 5.5): 5.32
ACD/BCF (pH 5.5): 5003.85
ACD/KOC (pH 5.5): 11341.97
ACD/LogD (pH 7.4): 5.78
ACD/BCF (pH 7.4): 14556.69
ACD/KOC (pH 7.4): 32994.91
Polar Surface Area: 48 Å2
Polarizability: 47.8±0.5 10-24cm3
Surface Tension: 53.1±3.0 dyne/cm
Molar Volume: 336.5±3.0 cm3

Click to predict properties on the Chemicalize site


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