ChemSpider 2D Image | CUDC-101 | C24H26N4O4

CUDC-101

  • Molecular FormulaC24H26N4O4
  • Average mass434.488 Da
  • Monoisotopic mass434.195404 Da
  • ChemSpider ID24650802

More details:

Validated by Experts, Validated by Users, Non-Validated, Removed by Users

1012054-59-9 [RN]
7-({4-[(3-Ethinylphenyl)amino]-7-methoxy-6-chinazolinyl}oxy)-N-hydroxyheptanamid [German] [ACD/IUPAC Name]
7-({4-[(3-Ethynylphenyl)amino]-7-methoxy-6-quinazolinyl}oxy)-N-hydroxyheptanamide [ACD/IUPAC Name]
7-({4-[(3-Éthynylphényl)amino]-7-méthoxy-6-quinazolinyl}oxy)-N-hydroxyheptanamide [French] [ACD/IUPAC Name]
7-({4-[(3-ethynylphenyl)amino]-7-methoxyquinazolin-6-yl}oxy)-N-hydroxyheptanamide
CUDC-101
Heptanamide, 7-[[4-[(3-ethynylphenyl)amino]-7-methoxy-6-quinazolinyl]oxy]-N-hydroxy- [ACD/Index Name]
[1012054-59-9] [RN]
1313875-12-5 [RN]
1A7Y9MP123
More...
  • Miscellaneous

    • Bio Activity:

      Cell Cycle/DNA Damage; JAK/STAT Signaling; Protein Tyrosine Kinase/RTK; MedChem Express HY-10223
      CUDC-101 is a potent multitargeted HDAC, EGFR and HER2 inhibitor with IC50 of 4.4, 2.4, and 15.7 nM, respectively. MedChem Express
      EGFR HDAC MedChem Express HY-10223

Predicted data is generated using the ACD/Labs Percepta Platform - PhysChem Module, version: 14.00

Density: 1.3±0.1 g/cm3
Boiling Point:
Vapour Pressure:
Enthalpy of Vaporization:
Flash Point:
Index of Refraction: 1.638
Molar Refractivity: 121.1±0.4 cm3
#H bond acceptors: 8
#H bond donors: 3
#Freely Rotating Bonds: 12
#Rule of 5 Violations: 0
ACD/LogP: 2.84
ACD/LogD (pH 5.5): 2.70
ACD/BCF (pH 5.5): 54.49
ACD/KOC (pH 5.5): 480.58
ACD/LogD (pH 7.4): 3.05
ACD/BCF (pH 7.4): 122.18
ACD/KOC (pH 7.4): 1077.51
Polar Surface Area: 106 Å2
Polarizability: 48.0±0.5 10-24cm3
Surface Tension: 67.8±5.0 dyne/cm
Molar Volume: 337.2±5.0 cm3

Click to predict properties on the Chemicalize site


Advertisement