ChemSpider 2D Image | GSK2033 | C29H28F3NO5S2

GSK2033

  • Molecular FormulaC29H28F3NO5S2
  • Average mass591.661 Da
  • Monoisotopic mass591.136108 Da
  • ChemSpider ID24668713

More details:

Validated by Experts, Validated by Users, Non-Validated, Removed by Users

1221277-90-2 [RN]
2,4,6-Trimethyl-N-[[3'-(methylsulfonyl)[1,1'-biphenyl]-4-yl]methyl]-N-[[5-(trifluoromethyl)-2-furanyl]methyl]benzenesulfonamide
2,4,6-Trimethyl-N-{[3'-(methylsulfonyl)-4-biphenylyl]methyl}-N-{[5-(trifluormethyl)-2-furyl]methyl}benzolsulfonamid [German] [ACD/IUPAC Name]
2,4,6-Trimethyl-N-{[3'-(methylsulfonyl)-4-biphenylyl]methyl}-N-{[5-(trifluoromethyl)-2-furyl]methyl}benzenesulfonamide [ACD/IUPAC Name]
2,4,6-Triméthyl-N-{[3'-(méthylsulfonyl)-4-biphénylyl]méthyl}-N-{[5-(trifluorométhyl)-2-furyl]méthyl}benzènesulfonamide [French] [ACD/IUPAC Name]
Benzenesulfonamide, 2,4,6-trimethyl-N-[[3'-(methylsulfonyl)[1,1'-biphenyl]-4-yl]methyl]-N-[[5-(trifluoromethyl)-2-furanyl]methyl]- [ACD/Index Name]
GSK2033
MFCD28396416
[1221277-90-2] [RN]
2,4,6-trimethyl-N-((3'-(methylsulfonyl)-[1,1'-biphenyl]-4-yl)methyl)-N-((5-(trifluoromethyl)furan-2-yl)methyl)benzenesulfonamide
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Validated by Experts, Validated by Users, Non-Validated, Removed by Users

CCRIS 4693 [DBID]
PubChem Substance ID 329825761 [DBID]
  • Experimental Physico-chemical Properties
  • Miscellaneous

    • Bio Activity:

      LXR-like Receptors Tocris Bioscience 5694
      Nuclear Receptors Tocris Bioscience 5694
      Potent LXR antagonist Tocris Bioscience 5694
      Potent LXR antagonist (pIC50 = 7.5). Enhances T-cell proliferation and blocks T 0901317-antiproliferative activity on T-cells. Cell permeable. Tocris Bioscience 5694

Predicted data is generated using the ACD/Labs Percepta Platform - PhysChem Module, version: 14.00

Density: 1.3±0.1 g/cm3
Boiling Point: 734.7±70.0 °C at 760 mmHg
Vapour Pressure: 0.0±2.4 mmHg at 25°C
Enthalpy of Vaporization: 107.2±3.0 kJ/mol
Flash Point: 398.1±35.7 °C
Index of Refraction: 1.572
Molar Refractivity: 147.6±0.4 cm3
#H bond acceptors: 6
#H bond donors: 0
#Freely Rotating Bonds: 9
#Rule of 5 Violations: 2
ACD/LogP: 6.62
ACD/LogD (pH 5.5): 6.18
ACD/BCF (pH 5.5): 29194.12
ACD/KOC (pH 5.5): 54681.83
ACD/LogD (pH 7.4): 6.18
ACD/BCF (pH 7.4): 29194.12
ACD/KOC (pH 7.4): 54681.83
Polar Surface Area: 101 Å2
Polarizability: 58.5±0.5 10-24cm3
Surface Tension: 44.6±3.0 dyne/cm
Molar Volume: 448.6±3.0 cm3

Click to predict properties on the Chemicalize site


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