ChemSpider 2D Image | 4,7-dichloro-3-hydroxy-3-[2-(4-methoxyphenyl)-2-oxoethyl]-1H-indol-2-one | C17H13Cl2NO4

4,7-dichloro-3-hydroxy-3-[2-(4-methoxyphenyl)-2-oxoethyl]-1H-indol-2-one

  • Molecular FormulaC17H13Cl2NO4
  • Average mass366.195 Da
  • Monoisotopic mass365.022156 Da
  • ChemSpider ID26232158

More details:

Validated by Experts, Validated by Users, Non-Validated, Removed by Users

1037184-44-3 [RN]
2H-Indol-2-one, 4,7-dichloro-1,3-dihydro-3-hydroxy-3-[2-(4-methoxyphenyl)-2-oxoethyl]- [ACD/Index Name]
4,7-Dichlor-3-hydroxy-3-[2-(4-methoxyphenyl)-2-oxoethyl]-1,3-dihydro-2H-indol-2-on [German] [ACD/IUPAC Name]
4,7-Dichloro-3-hydroxy-3-[2-(4-methoxyphenyl)-2-oxoethyl]-1,3-dihydro-2H-indol-2-one [ACD/IUPAC Name]
4,7-Dichloro-3-hydroxy-3-[2-(4-méthoxyphényl)-2-oxoéthyl]-1,3-dihydro-2H-indol-2-one [French] [ACD/IUPAC Name]
4,7-dichloro-3-hydroxy-3-[2-(4-methoxyphenyl)-2-oxoethyl]-1H-indol-2-one
4,7-dichloro-3-hydroxy-3-[2-(4-methoxyphenyl)-2-oxoethyl]-2,3-dihydro-1H-indol-2-one
(-)-YK-4-279
(+)-YK-4-279
[1037184-44-3] [RN]
More...

Validated by Experts, Validated by Users, Non-Validated, Removed by Users

PubChem Substance ID 329825761 [DBID]
  • Experimental Physico-chemical Properties
  • Miscellaneous

    • Target Organs:

      DNA/RNA Synthesis inhibitor TargetMol T2275

    • Bio Activity:

      Cell Biology Tocris Bioscience 4067
      Cell Metabolism Tocris Bioscience 4067
      DNA Damage/DNA Repair TargetMol T2275
      DNA, RNA and Protein Synthesis Tocris Bioscience 4067
      Inhibitor of RNA helicase A (RHA) Tocris Bioscience 4067
      Inhibitor of RNA Helicase A (RHA) binding to the oncogenic transciption factor EWS-FLI1. Inhibits Ewing's sarcoma family tumor (ESFT) cell growth; induces apoptosis. Tocris Bioscience 4067
      Others MedChem Express HY-14507
      RNA helicase A TargetMol T2275
      YK 4-279 is an inhibitor of RNA Helicase A (RHA) binding to the oncogenic transciption factor EWS-FLI1. MedChem Express http://www.medchemexpress.com/YK-4-279.html, HY-14507

Predicted data is generated using the ACD/Labs Percepta Platform - PhysChem Module, version: 14.00

Density: 1.5±0.1 g/cm3
Boiling Point: 608.9±55.0 °C at 760 mmHg
Vapour Pressure: 0.0±1.8 mmHg at 25°C
Enthalpy of Vaporization: 95.1±3.0 kJ/mol
Flash Point: 322.1±31.5 °C
Index of Refraction: 1.631
Molar Refractivity: 89.6±0.3 cm3
#H bond acceptors: 5
#H bond donors: 2
#Freely Rotating Bonds: 4
#Rule of 5 Violations: 0
ACD/LogP: 3.03
ACD/LogD (pH 5.5): 2.86
ACD/BCF (pH 5.5): 87.20
ACD/KOC (pH 5.5): 852.38
ACD/LogD (pH 7.4): 2.86
ACD/BCF (pH 7.4): 87.06
ACD/KOC (pH 7.4): 851.02
Polar Surface Area: 76 Å2
Polarizability: 35.5±0.5 10-24cm3
Surface Tension: 57.2±3.0 dyne/cm
Molar Volume: 251.4±3.0 cm3

Click to predict properties on the Chemicalize site


Advertisement