ChemSpider 2D Image | MRT67307 | C26H36N6O2

MRT67307

  • Molecular FormulaC26H36N6O2
  • Average mass464.603 Da
  • Monoisotopic mass464.289978 Da
  • ChemSpider ID26519068

More details:

Validated by Experts, Validated by Users, Non-Validated, Removed by Users

1190378-57-4 [RN]
Cyclobutanecarboxamide, N-[3-[[5-cyclopropyl-2-[[3-(4-morpholinylmethyl)phenyl]amino]-4-pyrimidinyl]amino]propyl]- [ACD/Index Name]
MRT67307
N-(3-{[5-CYCLOPROPYL-2-({3-[(MORPHOLIN-4-YL)METHYL]PHENYL}AMINO)PYRIMIDIN-4-YL]AMINO}PROPYL)CYCLOBUTANECARBOXAMIDE
N-{3-[(5-Cyclopropyl-2-{[3-(4-morpholinylmethyl)phenyl]amino}-4-pyrimidinyl)amino]propyl}cyclobutancarboxamid [German] [ACD/IUPAC Name]
N-{3-[(5-Cyclopropyl-2-{[3-(4-morpholinylmethyl)phenyl]amino}-4-pyrimidinyl)amino]propyl}cyclobutanecarboxamide [ACD/IUPAC Name]
N-{3-[(5-Cyclopropyl-2-{[3-(4-morpholinylméthyl)phényl]amino}-4-pyrimidinyl)amino]propyl}cyclobutanecarboxamide [French] [ACD/IUPAC Name]
N-{3-[(5-Cyclopropyl-2-{[3-(Morpholin-4-Ylmethyl)phenyl]amino}pyrimidin-4-Yl)amino]propyl}cyclobutanecarboxamide
[1190378-57-4] [RN]
1FV
More...
  • Experimental Physico-chemical Properties
  • Miscellaneous

    • Bio Activity:

      IKK MedChem Express HY-13018
      MRT67307 is a dual inhibitor of the IKKe and TBK-1. MedChem Express HY-13018
      MRT67307 is a dual inhibitor of the IKKe and TBK-1. IKKe and TBK-1 mediate the phosphorylation of interferon regulatory factor 3 (IRF3).;IC50 value:;Target: IKKe/TBK1 MedChem Express HY-13018
      NF-KB MedChem Express HY-13018
      NF-KB; MedChem Express HY-13018

Predicted data is generated using the ACD/Labs Percepta Platform - PhysChem Module, version: 14.00

Density: 1.3±0.1 g/cm3
Boiling Point:
Vapour Pressure:
Enthalpy of Vaporization:
Flash Point:
Index of Refraction: 1.652
Molar Refractivity: 133.8±0.3 cm3
#H bond acceptors: 8
#H bond donors: 3
#Freely Rotating Bonds: 11
#Rule of 5 Violations: 0
ACD/LogP: 1.30
ACD/LogD (pH 5.5): 0.51
ACD/BCF (pH 5.5): 1.00
ACD/KOC (pH 5.5): 4.01
ACD/LogD (pH 7.4): 2.63
ACD/BCF (pH 7.4): 52.62
ACD/KOC (pH 7.4): 527.02
Polar Surface Area: 91 Å2
Polarizability: 53.0±0.5 10-24cm3
Surface Tension: 67.5±3.0 dyne/cm
Molar Volume: 365.8±3.0 cm3

Click to predict properties on the Chemicalize site


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