ChemSpider 2D Image | STF-31 | C23H25N3O3S

STF-31

  • Molecular FormulaC23H25N3O3S
  • Average mass423.528 Da
  • Monoisotopic mass423.161652 Da
  • ChemSpider ID28467527

More details:

Validated by Experts, Validated by Users, Non-Validated, Removed by Users

4-({[(4-Tert-Butylphenyl)sulfonyl]amino}methyl)-N-(Pyridin-3-Yl)benzamide
4-[({[4-(2-Methyl-2-propanyl)phenyl]sulfonyl}amino)methyl]-N-(3-pyridinyl)benzamid [German] [ACD/IUPAC Name]
4-[({[4-(2-Methyl-2-propanyl)phenyl]sulfonyl}amino)methyl]-N-(3-pyridinyl)benzamide [ACD/IUPAC Name]
4-[({[4-(2-Méthyl-2-propanyl)phényl]sulfonyl}amino)méthyl]-N-(3-pyridinyl)benzamide [French] [ACD/IUPAC Name]
4-[(4-TERT-BUTYLBENZENESULFONAMIDO)METHYL]-N-(PYRIDIN-3-YL)BENZAMIDE
4-[[[[4-(1,1-dimethylethyl)phenyl]sulfonyl]amino]methyl]-N-3-pyridinyl-benzamide
724741-75-7 [RN]
Benzamide, 4-[[[[4-(1,1-dimethylethyl)phenyl]sulfonyl]amino]methyl]-N-3-pyridinyl- [ACD/Index Name]
MFCD04153828
STF-31
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Validated by Experts, Validated by Users, Non-Validated, Removed by Users

CCRIS 4693 [DBID]
PubChem Substance ID 329825761 [DBID]
  • Experimental Physico-chemical Properties
  • Miscellaneous

    • Target Organs:

      GLUT inhibitor TargetMol T2363

    • Bio Activity:

      Enzymes Tocris Bioscience 4484
      GLUT1 TargetMol T2363
      Inhibitor of GLUT1; inhibits glucose uptake in renal cell carcinoma (RCC) 4 cells. Activity causes necrotic cell death in von Hippel-Lindau (VHL)-deficient RCC cells. Also NAMPT inhibitor. Eliminates human pluripotent stem cells from culture with limited toxicity towards differentiated cells. Tocris Bioscience 4484
      Inhibitor of GLUT1; inhibits glucose uptake in renal cell carcinoma (RCC) 4 cells. Activity causes necrotic cell death in von Hippel-Lindau (VHL)-deficient RCC cells. Also NAMPT inhibitor. Eliminates human pluripotent stem cells from culture with limited toxicity towards differentiated cells. Tocris Bioscience 4484
      Metabolism TargetMol T2363
      NAMPT Tocris Bioscience 4484
      NAMPT inhibitor; also GLUT1 inhibitor Tocris Bioscience 4484
      Others MedChem Express HY-18728
      STF-31 is an inhibitor of glucose transporter 1 (GLUT1, IC50 = 1 ?M).; IC50 value: 1 ?M; Target: GLUT1; in vitro: STF 31 is a glucose uptake inhibitor in RCC (renal cell carcinoma) 4 cells. MedChem Express HY-18728
      Transferases Tocris Bioscience 4484

Predicted data is generated using the ACD/Labs Percepta Platform - PhysChem Module, version: 14.00

Density: 1.2±0.1 g/cm3
Boiling Point:
Vapour Pressure:
Enthalpy of Vaporization:
Flash Point:
Index of Refraction: 1.612
Molar Refractivity: 118.0±0.4 cm3
#H bond acceptors: 6
#H bond donors: 2
#Freely Rotating Bonds: 7
#Rule of 5 Violations: 0
ACD/LogP: 3.88
ACD/LogD (pH 5.5): 3.51
ACD/BCF (pH 5.5): 266.63
ACD/KOC (pH 5.5): 1829.63
ACD/LogD (pH 7.4): 3.57
ACD/BCF (pH 7.4): 302.24
ACD/KOC (pH 7.4): 2074.01
Polar Surface Area: 97 Å2
Polarizability: 46.8±0.5 10-24cm3
Surface Tension: 54.2±3.0 dyne/cm
Molar Volume: 339.5±3.0 cm3

Click to predict properties on the Chemicalize site


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