ChemSpider 2D Image | Bioymifi | C22H12BrN3O4S

Bioymifi

  • Molecular FormulaC22H12BrN3O4S
  • Average mass494.317 Da
  • Monoisotopic mass492.973175 Da
  • ChemSpider ID29785800

  • Double-bond stereo - Double-bond stereo

More details:

Validated by Experts, Validated by Users, Non-Validated, Removed by Users

1420071-30-2 [RN]
1H-Isoindole-1,3(2H)-dione, 5-[5-[(Z)-[3-(4-bromophenyl)-2-imino-4-oxo-5-thiazolidinylidene]methyl]-2-furanyl]- [ACD/Index Name]
5-(5-{(Z)-[3-(4-Bromophenyl)-2-imino-4-oxo-1,3-thiazolidin-5-ylidene]methyl}-2-furyl)-1H-isoindole-1,3(2H)-dione [ACD/IUPAC Name]
5-(5-{(Z)-[3-(4-Bromophényl)-2-imino-4-oxo-1,3-thiazolidin-5-ylidène]méthyl}-2-furyl)-1H-isoindole-1,3(2H)-dione [French] [ACD/IUPAC Name]
5-(5-{(Z)-[3-(4-Bromphenyl)-2-imino-4-oxo-1,3-thiazolidin-5-yliden]methyl}-2-furyl)-1H-isoindol-1,3(2H)-dion [German] [ACD/IUPAC Name]
5-(5-{[(5Z)-3-(4-bromophenyl)-2-imino-4-oxo-1,3-thiazolidin-5-ylidene]methyl}furan-2-yl)-2,3-dihydro-1H-isoindole-1,3-dione
5-(5-{[(5Z)-3-(4-bromophenyl)-2-imino-4-oxo-1,3-thiazolidin-5-ylidene]methyl}furan-2-yl)-2H-isoindole-1,3-dione
Bioymifi
(2-(4-(tert-Butoxycarbonyl)piperazin-1-yl)pyridin-3-yl)boronic acid
(Z)-5-(5-((3-(4-Bromophenyl)-2-imino-4-oxothiazolidin-5-ylidene)methyl)furan-2-yl)isoindoline-1,3-dione
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  • Experimental Physico-chemical Properties
  • Miscellaneous

    • Bio Activity:

      Apoptosis MedChem Express HY-18377
      Apoptosis; MedChem Express HY-18377
      Bioymifi(DR5 Activator) is the first novel and potent small-molecule activatior of the TRAIL receptor DR5 in human cancer cells. MedChem Express
      Bioymifi(DR5 Activator) is the first novel and potent small-molecule activatior of the TRAIL receptor DR5 in human cancer cells.; IC50 value:; Target: ; In comparison with A2C2, bioymifi was able to promote cell death without the need for the Smac mimetic in T98G cells. MedChem Express HY-18377
      Cytokine Receptors Tocris Bioscience 5372
      DR5 (TRAIL receptor) agonist. Directly binds extracellular domain of DR5 (Kd = 1.2 muM) and induces the formation of DR5 aggregates. Induces apoptosis of glioblastoma cells. Tocris Bioscience 5372
      DR5 (TRAIL receptor) agonist; induces apoptosis Tocris Bioscience 5372
      Enzyme-Linked Receptors Tocris Bioscience 5372
      TNF alpha MedChem Express HY-18377

Predicted data is generated using the ACD/Labs Percepta Platform - PhysChem Module, version: 14.00

Density: 1.8±0.1 g/cm3
Boiling Point:
Vapour Pressure:
Enthalpy of Vaporization:
Flash Point:
Index of Refraction: 1.791
Molar Refractivity: 119.4±0.5 cm3
#H bond acceptors: 7
#H bond donors: 2
#Freely Rotating Bonds: 3
#Rule of 5 Violations: 0
ACD/LogP: 4.80
ACD/LogD (pH 5.5): 3.24
ACD/BCF (pH 5.5): 169.45
ACD/KOC (pH 5.5): 1371.34
ACD/LogD (pH 7.4): 3.23
ACD/BCF (pH 7.4): 168.46
ACD/KOC (pH 7.4): 1363.35
Polar Surface Area: 129 Å2
Polarizability: 47.3±0.5 10-24cm3
Surface Tension: 71.9±7.0 dyne/cm
Molar Volume: 281.6±7.0 cm3

Click to predict properties on the Chemicalize site


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