ChemSpider 2D Image | zolasartan | C24H20BrClN6O3

zolasartan

  • Molecular FormulaC24H20BrClN6O3
  • Average mass555.811 Da
  • Monoisotopic mass554.046875 Da
  • ChemSpider ID65141

More details:

Validated by Experts, Validated by Users, Non-Validated, Removed by Users

1-({3-Brom-2-[2-(2H-tetrazol-5-yl)phenyl]-1-benzofuran-5-yl}methyl)-2-butyl-4-chlor-1H-imidazol-5-carbonsäure [German] [ACD/IUPAC Name]
1-({3-Bromo-2-[2-(2H-tetrazol-5-yl)phenyl]-1-benzofuran-5-yl}methyl)-2-butyl-4-chloro-1H-imidazole-5-carboxylic acid [ACD/IUPAC Name]
145781-32-4 [RN]
1H-Imidazole-5-carboxylic acid, 1-[[3-bromo-2-[2-(2H-tetrazol-5-yl)phenyl]-5-benzofuranyl]methyl]-2-butyl-4-chloro- [ACD/Index Name]
Acide 1-({3-bromo-2-[2-(2H-tétrazol-5-yl)phényl]-1-benzofuran-5-yl}méthyl)-2-butyl-4-chloro-1H-imidazole-5-carboxylique [French] [ACD/IUPAC Name]
zolasartan [INN]
zolasartan [French] [INN]
zolasartán [Spanish] [INN]
zolasartanum [Latin] [INN]
золасартан [Russian] [INN]
More...

Validated by Experts, Validated by Users, Non-Validated, Removed by Users

7204 [DBID]
GR 117289 [DBID]
  • Miscellaneous

    • Chemical Class:

      A member of the class of 1-benzofurans that is 3-bromo-1-benzofuran which is substituted by a 2-(1H-tetrazol-5-yl)phenyl group at position 2 and by a (2-butyl-5-carboxy-4-chloro-1H-imidazol-1-yl)methy l group at position 5. It is an angiotensin II receptor type 1 (AT1) antagonist and was in clinical trials for the treatment of hypertension (now discontinued). ChEBI CHEBI:149761

Predicted data is generated using the ACD/Labs Percepta Platform - PhysChem Module, version: 14.00

Density: 1.7±0.1 g/cm3
Boiling Point: 773.3±70.0 °C at 760 mmHg
Vapour Pressure: 0.0±2.8 mmHg at 25°C
Enthalpy of Vaporization: 118.1±3.0 kJ/mol
Flash Point: 421.5±35.7 °C
Index of Refraction: 1.745
Molar Refractivity: 134.7±0.5 cm3
#H bond acceptors: 9
#H bond donors: 2
#Freely Rotating Bonds: 8
#Rule of 5 Violations: 2
ACD/LogP: 5.97
ACD/LogD (pH 5.5): 1.62
ACD/BCF (pH 5.5): 1.18
ACD/KOC (pH 5.5): 3.16
ACD/LogD (pH 7.4): 1.32
ACD/BCF (pH 7.4): 1.00
ACD/KOC (pH 7.4): 1.60
Polar Surface Area: 123 Å2
Polarizability: 53.4±0.5 10-24cm3
Surface Tension: 62.8±7.0 dyne/cm
Molar Volume: 332.3±7.0 cm3

Click to predict properties on the Chemicalize site


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