ChemSpider 2D Image | Oglemilast | C20H13Cl2F2N3O5S

Oglemilast

  • Molecular FormulaC20H13Cl2F2N3O5S
  • Average mass516.302 Da
  • Monoisotopic mass514.992126 Da
  • ChemSpider ID9562320

More details:

Validated by Experts, Validated by Users, Non-Validated, Removed by Users

1-Dibenzofurancarboxamide, N-(3,5-dichloro-4-pyridinyl)-4-(difluoromethoxy)-8-[(methylsulfonyl)amino]- [ACD/Index Name]
778576-62-8 [RN]
N-(3,5-Dichlor-4-pyridinyl)-4-(difluormethoxy)-8-[(methylsulfonyl)amino]dibenzo[b,d]furan-1-carboxamid [German] [ACD/IUPAC Name]
N-(3,5-Dichloro-4-pyridinyl)-4-(difluoromethoxy)-8-[(methylsulfonyl)amino]dibenzo[b,d]furan-1-carboxamide [ACD/IUPAC Name]
N-(3,5-Dichloro-4-pyridinyl)-4-(difluorométhoxy)-8-[(méthylsulfonyl)amino]dibenzo[b,d]furane-1-carboxamide [French] [ACD/IUPAC Name]
oglemilast [Spanish] [INN]
Oglemilast [INN]
oglémilast [French] [INN]
oglemilastum [Latin] [INN]
оглемиласт [Russian] [INN]
More...

Validated by Experts, Validated by Users, Non-Validated, Removed by Users

67GXQ6WCC6 [DBID]
8675 [DBID]
UNII-67GXQ6WCC6 [DBID]
UNII:67GXQ6WCC6 [DBID]
  • Experimental Physico-chemical Properties
  • Miscellaneous

    • Bio Activity:

      Immunology/Inflammation MedChem Express HY-15178
      Immunology/Inflammation; Metabolic Enzyme/Protease; MedChem Express HY-15178
      Oglemilast(GRC3886) is a potent PDE4 inhibitor, under clinical studies in the treatment of allergen-induced asthma. MedChem Express
      Oglemilast(GRC3886) is a potent PDE4 inhibitor, under clinical studies in the treatment of allergen-induced asthma.; IC50 value:; Target: PDE4 MedChem Express HY-15178
      Oglemilast(GRC3886) is a potent PDE4 inhibitor, under clinical studies in the treatment of allergen-induced asthma.;IC50 value:;Target: PDE4 MedChem Express HY-15178
      PDE4 MedChem Express HY-15178

Predicted data is generated using the ACD/Labs Percepta Platform - PhysChem Module, version: 14.00

Density: 1.7±0.1 g/cm3
Boiling Point:
Vapour Pressure:
Enthalpy of Vaporization:
Flash Point:
Index of Refraction: 1.684
Molar Refractivity: 118.6±0.4 cm3
#H bond acceptors: 8
#H bond donors: 2
#Freely Rotating Bonds: 6
#Rule of 5 Violations: 1
ACD/LogP: 4.56
ACD/LogD (pH 5.5): 4.09
ACD/BCF (pH 5.5): 752.87
ACD/KOC (pH 5.5): 3960.49
ACD/LogD (pH 7.4): 3.63
ACD/BCF (pH 7.4): 262.42
ACD/KOC (pH 7.4): 1380.45
Polar Surface Area: 119 Å2
Polarizability: 47.0±0.5 10-24cm3
Surface Tension: 65.9±3.0 dyne/cm
Molar Volume: 312.2±3.0 cm3

Click to predict properties on the Chemicalize site


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