Accessed:

Methotrexate

Molecular formula:	C20H22N8O5
Average mass:	454.447
Monoisotopic mass:	454.171316
ChemSpider ID:	112728

1 of 1 defined stereocentres

Wikipedia

Structural identifiers

Names

Names and synonyms

Verified

(+)-Amethopterin

(2S)-2-[(4-{[(2,4-diaminopteridin-6-yl)methyl](methyl)amino}phenyl)formamido]pentanedioic acid

(2S)-2-{[(4-{[(2,4-Diaminopteridin-6-yl)methyl](methyl)amino}phenyl)carbonyl]amino}pentandisäure

[German]

(2S)-2-{[(4-{[(2,4-diaminopteridin-6-yl)methyl](methyl)amino}phenyl)carbonyl]amino}pentanedioic acid

262-213-7

[EINECS]

4-amino-10-methylfolic acid

4-Amino-N10-methylfolic Acid

4-Amino-N10-methylpteroylglutamic Acid

59-05-2

[RN]

70669

[Beilstein]

acide (2S)-2-{[(4-{[(2,4-diaminoptéridin-6-yl)méthyl](méthyl)amino}phényl)carbonyl]amino}pentanedioïque

[French]

Acide N-(4-{[(2,4-diamino-6-ptéridinyl)méthyl](méthyl)amino}benzoyl)-L-glutamique

[French]

[ACD/IUPAC Name]

Amethopterine

Antifolan

L-(+)-N-[p-[[(2,4-Diamino-6-pteridinyl)methyl]methylamino]benzoyl]glutamic Acid

L-Amethopterin

L-Glutamic acid, N-(4-(((2,4-diamino-6-pteridinyl)methyl)methylamino)benzoyl)-

L-Glutamic acid, N-[4-[[(2,4-diamino-6-pteridinyl)methyl]methylamino]benzoyl]-

[ACD/Index Name]

L-Methotrexate

Methotrexate

[Wiki]

[INN] [BAN] [USAN] [USP]

méthotrexate

[French]

[INN]

methotrexatum

[Latin]

[INN]

Methylaminopterin

Metotrexato

[Spanish]

[INN]

MFCD00064370

[MDL number]

MTX

N-(4-{[(2,4-Diamino-6-pteridinyl)methyl](methyl)amino}benzoyl)-L-glutamic acid

[ACD/IUPAC Name]

N-(4-{[(2,4-Diamino-6-pteridinyl)methyl](methyl)amino}benzoyl)-L-glutaminsäure

[German]

[ACD/IUPAC Name]

N-(4-{[(2,4-Diaminopteridin-6-yl)methyl](methyl)amino}benzoyl)-L-glutamic acid

α-Methopterin

метотрексат

[Russian]

[INN]

ميثوتريكسات

[Arabic]

[INN]

甲氨蝶呤

[Chinese]

[INN]

Unverified

(+)-4-Amino-10-methylfolic acid

(2S)-2-[[4-[(2,4-diaminopteridin-6-yl)methyl-methyl-amino]benzoyl]amino]glutaric acid

(2S)-2-[[4-[(2,4-diaminopteridin-6-yl)methyl-methyl-amino]benzoyl]amino]pentanedioic acid

(2S)-2-[[4-[(2,4-diaminopteridin-6-yl)methyl-methyl-amino]phenyl]carbonylamino]pentanedioic acid

(2S)-2-[[4-[(2,4-Diaminopteridin-6-yl)methyl-methylamino]benzoyl]amino]pentanedioic acid

(2S)-2-[[[4-[(2,4-diamino-6-pteridinyl)methyl-methylamino]phenyl]-oxomethyl]amino]pentanedioic acid

(4-(((2,4-diaminopteridin-6-yl)methyl)(methyl)amino)benzoyl)-L-glutamic acid

(S)-2-(4-(((2,4-diaminopteridin-6-yl)methyl)(methyl)amino)benzamido)pentanedioic acid

(S)-2-(4-(((2,4-Diaminopteridin-6-yl)methyl)-(methyl)amino)benzamido)pentanedioic acid

(S)-2-{4-[(2,4-Diamino-pteridin-6-ylmethyl)-methyl-amino]-benzoylamino}-pentanedioic acid

133073-73-1

[RN]

1959-5-2

4-amino-10-methylfolic acid; Amethopterin; Methotrexat; Méthotrexate; Methotrexatum; Metotrexato; MTX

4-amino-N(10)-methylpteroylglutamic acid

432545-63-6

[RN]

5-Amino-1-methyl-1H-benzimidazole-2-butanoic acid ethyl ester

59-05-2 (free acid)

6PGD_HUMAN

95%

[³H]methotrexate

A-Methopterin

Abitrexate

[Trade name]

Abitrexate; Alltrex; Artrait; Atrexel; Bendatrexat; Carditrex; Dermotrex; Ebetrex; Emtexate; Ledertrexate; Maxtrex; Meisusheng; Mexate; Rheumatrex; Trexan; Zexate

Abitrexate;Rheumatrex;Amethopterin;Trexall;CL14377;WR19039

Abitrexate®

Alltrex

[Trade name]

Amethopterin

[Wiki]

ametopterina

AMPL_YEAST

Arbitrexate

Artrait

[Trade name]

Atrexel

[Trade name]

B2L11_HUMAN

Bcl-2-like protein 11

Bendatrexat

[Trade name]

Carditrex

[Trade name]

Dermotrex

[Trade name]

Dihydrofolate reductase

DRTS_TOXGO

DYR_BOVIN

DYR_ECOLI

DYR_HUMAN

DYR_MYCTU

Ebetrex

[Trade name]

Emtexate

[Trade name]

Extexate

FOLEX

FOLEX PFS

Folex-Pfs

G6PD_HUMAN

Glucose-6-phosphate 1-dehydrogenase

Glutamic acid, N-(p-(((2,4-diamino-6-pteridinyl)methyl)methylamino)benzoyl)-, L-

Glutamic acid, N-[p-[[(2,4-diamino-6-pteridinyl)methyl] methylamino]benzoyl]-, L-(+)-

Hdmtx

IDI1_000114

IMA1_HUMAN

Importin subunit α-1

Intradose-MTX

L-(+)-N-(p-(((2,4-Diamino-6-pteridinyl)methyl)methylamino)benzoyl)glutamic acid

Ledertrexate

[Trade name]

Lopac0_000020

Maxtrex

[Wiki]

[Trade name]

Meisusheng

[Trade name]

Metatrexan

METH_HUMAN

Methionine synthase

Methopterin

Methotextrate

Methotrate

Methotrexat

Methotrexat-Ebewe

Méthotrexate

Methotrexatum

Methotrexic acid

Methoxtrexate

Methylaminopterine

Methylaminopterinum

Metolate

Metotrexato

Mexate

[Trade name]

MEXATE-AQ

MFCD00150847

[MDL number]

MTX - METHOTREXATE

N-(4-(((2,4-Diamino-6-pteridinyl)methyl)methylamino)benzoyl)-L-glutamicacid

N-(4-{[(2,4-Diaminopteridin-1-Ium-6-Yl)methyl](Methyl)amino}benzoyl)-L-Glutamic Acid

N-(p-(((2,4-Diamino-6-pteridinyl)methyl)methylamino)benzoyl)-L-(+)-glutamic acid

N-[(4-{[(2,4-diaminopteridin-6-yl)methyl](methyl)amino}phenyl)carbonyl]-L-glutamic acid

N-[4-[[(2,4-Diamino-6-pteridinyl)methyl] methylamino]benzoyl]-L-glutamic acid

N-[4-[[(2,4-Diamino-6-pteridinyl)methyl]methylamino]benzoyl]-L-glutamic acid

N-{4-[[(2,4-diamino-6-pteridinyl)methyl](methyl)amino]benzoyl}-L-glutamic acid

NCOA1_HUMAN

NCOA3_HUMAN

Nuclear receptor coactivator 1

Nuclear receptor coactivator 3

O30463_MYCAV

Otrexup

Prestwick2_000135

PUR9_HUMAN

Q81E04_BACCR

Q81R22_BACAN

Rasuvo®

Rheumatrex

[Trade name]

Rheumatrex Dose Pack

SMP2_000020

Spectrum5_000958

T66 BN DN GN JNJ CZ EZ H1N1&R DVMYVQ2VQ

[WLN]

Tegument protein VP16

Thymidylate synthase

TLR4_HUMAN

Toll-like receptor 4

TREXALL

Trexan

[Trade name]

TYSY_ECOLI

TYSY_HUMAN

Vacuolar aminopeptidase 1

VP16_HHV11

Zexate

Database IDs