ChemSpider 2D Image | BIO-acetoxime | C18H12BrN3O3

BIO-acetoxime

  • Molecular FormulaC18H12BrN3O3
  • Average mass398.210 Da
  • Monoisotopic mass397.006195 Da
  • ChemSpider ID24606059

  • Double-bond stereo - Double-bond stereo

More details:

Validated by Experts, Validated by Users, Non-Validated, Removed by Users

(3E)-3-[(3E)-3-(Acetoxyimino)-1,3-dihydro-2H-indol-2-yliden]-6-brom-1,3-dihydro-2H-indol-2-on [German] [ACD/IUPAC Name]
(3E)-3-[(3E)-3-(Acetoxyimino)-1,3-dihydro-2H-indol-2-ylidene]-6-bromo-1,3-dihydro-2H-indol-2-one [ACD/IUPAC Name]
(3E)-3-[(3E)-3-(Acétoxyimino)-1,3-dihydro-2H-indol-2-ylidène]-6-bromo-1,3-dihydro-2H-indol-2-one [French] [ACD/IUPAC Name]
2H-Indol-2-one, 3-[(3E)-3-[(acetyloxy)imino]-1,3-dihydro-2H-indol-2-ylidene]-6-bromo-1,3-dihydro-, (3E)- [ACD/Index Name]
740841-15-0 [RN]
BIO-acetoxime
(2'Z,3'E)-6-Bromoindirubin-3'-acetoxime
[667463-85-6] [RN]
1044661-40-6 [RN]
2H-Indol-2-one, 3-[3-[(acetyloxy)imino]-1,3-dihydro-2H-indol-2-ylidene]-6-bro...
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  • Experimental Physico-chemical Properties
  • Miscellaneous

    • Bio Activity:

      Enzymes Tocris Bioscience 3874
      Glycogen Synthase Kinase 3 Tocris Bioscience 3874
      Kinases Tocris Bioscience 3874
      Selective GSK-3?/? inhibitor Tocris Bioscience 3874
      Selective GSK-3?/? inhibitor (IC50 values are 0.01, 2.4, 4.3 and 63 ?M for GSK-3?/?, CDK5/p25, CDK2/cyclin A and CDK1/cyclin B respectively). Induces Wnt signaling and inhibits CD8+ T cell effector di fferentiation. Tocris Bioscience 3874
      Selective GSK-3?/? inhibitor (IC50 values are 0.01, 2.4, 4.3 and 63 ?M for GSK-3?/?, CDK5/p25, CDK2/cyclin A and CDK1/cyclin B respectively). Induces Wnt signaling and inhibits CD8+ T cell effector differentiation. Tocris Bioscience 3874
      Selective GSK-3alpha/beta inhibitor Tocris Bioscience 3874
      Selective GSK-3alpha/beta inhibitor (IC50 values are 0.01, 2.4, 4.3 and 63 muM for GSK-3alpha/beta, CDK5/p25, CDK2/cyclin A and CDK1/cyclin B respectively). Induces Wnt signaling and inhibits CD8+ T cell effector differentiation. Tocris Bioscience 3874

Predicted data is generated using the ACD/Labs Percepta Platform - PhysChem Module, version: 14.00

Density: 1.7±0.1 g/cm3
Boiling Point:
Vapour Pressure:
Enthalpy of Vaporization:
Flash Point:
Index of Refraction: 1.741
Molar Refractivity: 94.9±0.5 cm3
#H bond acceptors: 6
#H bond donors: 2
#Freely Rotating Bonds: 2
#Rule of 5 Violations: 0
ACD/LogP: 2.37
ACD/LogD (pH 5.5): 2.98
ACD/BCF (pH 5.5): 108.32
ACD/KOC (pH 5.5): 995.48
ACD/LogD (pH 7.4): 2.97
ACD/BCF (pH 7.4): 106.76
ACD/KOC (pH 7.4): 981.13
Polar Surface Area: 80 Å2
Polarizability: 37.6±0.5 10-24cm3
Surface Tension: 60.6±7.0 dyne/cm
Molar Volume: 235.1±7.0 cm3

Click to predict properties on the Chemicalize site


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