Filgotinib

1206161-97-8

3XVL385Q0M

Cyclopropanecarboxamide, N-[5-[4-[(1,1-dioxido-4-thiomorpholinyl)methyl]phenyl][1,2,4]triazolo[1,5-a]pyridin-2-yl]-

Filgotinib

N-(5-(4-((1,1-dioxidothiomorpholino)methyl)phenyl)-[1,2,4]triazolo[1,5-a]pyridin-2-yl)cyclopropanecarboxamide

N-(5-{4-[(1,1-Dioxido-4-thiomorpholinyl)methyl]phenyl}[1,2,4]triazolo[1,5-a]pyridin-2-yl)cyclopropancarboxamid

N-(5-{4-[(1,1-Dioxido-4-thiomorpholinyl)methyl]phenyl}[1,2,4]triazolo[1,5-a]pyridin-2-yl)cyclopropanecarboxamide

N-(5-{4-[(1,1-Dioxydo-4-thiomorpholinyl)méthyl]phényl}[1,2,4]triazolo[1,5-a]pyridin-2-yl)cyclopropanecarboxamide

1206101-20-3

2041095-50-3

95%

CP1A2_HUMAN

CP2B6_HUMAN

CP2C8_HUMAN

CP2C9_HUMAN

CP2CJ_HUMAN

CP2D6_HUMAN

CP3A4_HUMAN

Cyclopropanecarboxamide, N-[5-[4-[(1,1-dioxido-4-thiomorpholinyl)methyl]phenyl][1,2,4]triazolo[1,5-a]pyridin-2-yl]-N-(5-(4-((1,1-dioxidothiomorpholino)methyl)phenyl)-[1,2,4]triazolo[1,5-a]pyridin-2-yl)cyclopropanecarboxamide

Cytochrome P450 1A2

Cytochrome P450 2B6

Cytochrome P450 2C19

Cytochrome P450 2C8

Cytochrome P450 2C9

Cytochrome P450 2D6

Cytochrome P450 3A4

Filgotinib (GLPG0634)

Filgotinib(glpg0634)

Filgotinib-d4

Filgotinib; GLPG 0634; GLPG-0634

filgotinibum

GLPG0634 analogue

JAK1_HUMAN

JAK2_HUMAN

JAK3/JAK1

JAK3_HUMAN

MFCD20527867

N-(5-(4-((1,1-Dioxidothiomorpholino)methyl)phenyl)[1,2,4]triazolo[1,5-a]pyridin-2-yl)cyclopropanecarboxamide

N-(5-{4-[(1,1-dioxo-1λ6-thiomorpholin-4-yl)methyl]phenyl}-[1,2,4]triazolo[1,5-a]pyridin-2-yl)cyclopropanecarboxamide

N-[5-[4-[(1,1-dioxido-4-thiomorpholinyl)methyl]phenyl][1,2,4]triazolo[1,5-a]pyridin-2-yl]-cyclopropanecarboxamide

N-[5-[4-[(1,1-Dioxido-4-thiomorpholinyl)methyl]phenyl][1,2,4]triazolo[1,5-a]pyridin-2-yl]cyclopropanecarboxamide

N-[5-[4-[(1,1-dioxo-1,4-thiazinan-4-yl)methyl]phenyl]-[1,2,4]triazolo[1,5-a]pyridin-2-yl]cyclopropanecarboxamide

Tasocitinib

TYK2_HUMAN

Tyrosine-protein kinase JAK1

Tyrosine-protein kinase JAK1 [850-1154]

Tyrosine-protein kinase JAK1 [866-1154]

Tyrosine-protein kinase JAK2

Tyrosine-protein kinase JAK2 [808-1132]

Tyrosine-protein kinase JAK3

Tyrosine-protein kinase JAK3 [781-1124]

Tyrosine-protein kinase JAK3 [811-1124]

US8563545, 20

филготиниб

فيلغوتينيب

非戈替尼