AGERAFENIB

1-{3-[(6,7-Dimethoxy-4-chinazolinyl)oxy]phenyl}-3-[5-(1,1,1-trifluor-2-methyl-2-propanyl)-1,2-oxazol-3-yl]harnstoff

1-{3-[(6,7-Dimethoxy-4-quinazolinyl)oxy]phenyl}-3-[5-(1,1,1-trifluoro-2-methyl-2-propanyl)-1,2-oxazol-3-yl]urea

1-{3-[(6,7-Diméthoxy-4-quinazolinyl)oxy]phényl}-3-[5-(1,1,1-trifluoro-2-méthyl-2-propanyl)-1,2-oxazol-3-yl]urée

1-{3-[(6,7-dimethoxyquinazolin-4-yl)oxy]phenyl}-3-[5-(1,1,1-trifluoro-2-methylpropan-2-yl)-1,2-oxazol-3-yl]urea

1188910-76-0

78I4VEX88N

AGERAFENIB

Urea, N-[3-[(6,7-dimethoxy-4-quinazolinyl)oxy]phenyl]-N′-[5-(2,2,2-trifluoro-1,1-dimethylethyl)-3-isoxazolyl]-

1-(3-((6,7-dimethoxyquinazolin-4-yl)oxy)phenyl)-3-(5-(1,1,1-trifluoro-2-methylpropan-2-yl)isoxazol-3-yl)urea

1-(3-(6,7-Dimethoxyquinazolin-4-yloxy)phenyl)-3-(5-(1,1,1-trifluoro-2-methylpropan-2-yl)isoxazol-3-yl)urea

1-[3-(6,7-dimethoxyquinazolin-4-yl)oxyphenyl]-3-[5-(1,1,1-trifluoro-2-methylpropan-2-yl)-1,2-oxazol-3-yl]urea

1188910-76-0 (free base)

ABL1_HUMAN

Agerafenib (RXDX-105)

Agerafenib; RXDX105

BRAF_HUMAN

CCDC6_HUMAN

CEP 32496;CEP32496

Coiled-coil domain-containing protein 6

EPHA2_HUMAN

Ephrin type-A receptor 2

Ephrin type-A receptor 2 [596-900]

KIT_HUMAN

MFCD22124524

N-​[3-​[(6,​7-​dimethoxy-​4-​quinazolinyl)​oxy]​phenyl]​-​N′-​[5-​(2,​2,​2-​trifluoro-​1,​1-​dimethylethyl)​-​3-​isoxazolyl]​-urea

NCOA4_HUMAN

Nuclear receptor coactivator 4

RAF1_HUMAN

RET_HUMAN

RXDX-105 (CEP-32496)

Serine/threonine-protein kinase B-raf

Tyrosine-protein kinase ABL1

VGFR1_HUMAN

VGFR2_HUMAN