ChemSpider 2D Image | GNE-617 | C21H15F2N3O3S

GNE-617

  • Molecular FormulaC21H15F2N3O3S
  • Average mass427.424 Da
  • Monoisotopic mass427.080231 Da
  • ChemSpider ID30821091

More details:

Validated by Experts, Validated by Users, Non-Validated, Removed by Users

1362154-70-8 [RN]
GNE-617
Imidazo[1,2-a]pyridine-6-carboxamide, N-[[4-[(3,5-difluorophenyl)sulfonyl]phenyl]methyl]- [ACD/Index Name]
N-{[4-(3,5-difluorobenzenesulfonyl)phenyl]methyl}imidazo[1,2-a]pyridine-6-carboxamide
N-{4-[(3,5-Difluorophenyl)sulfonyl]benzyl}imidazo[1,2-a]pyridine-6-carboxamide [ACD/IUPAC Name]
N-{4-[(3,5-Difluorophényl)sulfonyl]benzyl}imidazo[1,2-a]pyridine-6-carboxamide [French] [ACD/IUPAC Name]
N-{4-[(3,5-Difluorphenyl)sulfonyl]benzyl}imidazo[1,2-a]pyridin-6-carboxamid [German] [ACD/IUPAC Name]
BS-15263
GNE 617
GNE617
More...
  • Experimental Physico-chemical Properties
  • Miscellaneous

    • Bio Activity:

      GNE-617 is a novel and specific Nampt inhibitor with an IC50 of 18.9 nM in A549 cell. MedChem Express
      GNE-617 is a novel and specific Nampt inhibitor with an IC50 of 18.9 nM in A549 cell.; IC50 value: 18.9 nM (in Hela) [1]; Target: Nampt MedChem Express HY-15766
      GNE-617 is a novel and specific Nampt inhibitor with an IC50 of 18.9 nM in A549 cell.;IC50 value: 18.9 nM (in Hela) [1];Target: Nampt MedChem Express HY-15766
      Metabolic Enzyme/Protease; MedChem Express HY-15766
      Nampt MedChem Express HY-15766
      Others MedChem Express HY-15766

Predicted data is generated using the ACD/Labs Percepta Platform - PhysChem Module, version: 14.00

Density: 1.4±0.1 g/cm3
Boiling Point:
Vapour Pressure:
Enthalpy of Vaporization:
Flash Point:
Index of Refraction: 1.651
Molar Refractivity: 109.5±0.5 cm3
#H bond acceptors: 6
#H bond donors: 1
#Freely Rotating Bonds: 5
#Rule of 5 Violations: 0
ACD/LogP: 3.19
ACD/LogD (pH 5.5): 2.10
ACD/BCF (pH 5.5): 20.87
ACD/KOC (pH 5.5): 269.94
ACD/LogD (pH 7.4): 2.29
ACD/BCF (pH 7.4): 32.33
ACD/KOC (pH 7.4): 418.13
Polar Surface Area: 89 Å2
Polarizability: 43.4±0.5 10-24cm3
Surface Tension: 52.3±7.0 dyne/cm
Molar Volume: 300.0±7.0 cm3

Click to predict properties on the Chemicalize site


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