ChemSpider 2D Image | SU 14813 | C23H27FN4O4

SU 14813

  • Molecular FormulaC23H27FN4O4
  • Average mass442.483 Da
  • Monoisotopic mass442.201630 Da
  • ChemSpider ID32701840

  • Double-bond stereo - Double-bond stereo

    defined stereocentres - 1 of 1 defined stereocentres

More details:

Validated by Experts, Validated by Users, Non-Validated, Removed by Users

1H-Pyrrole-3-carboxamide, 5-[(E)-(5-fluoro-1,2-dihydro-2-oxo-3H-indol-3-ylidene)methyl]-N-[(2S)-2-hydroxy-3-(4-morpholinyl)propyl]-2,4-dimethyl- [ACD/Index Name]
5-[(E)-(5-Fluor-2-oxo-1,2-dihydro-3H-indol-3-yliden)methyl]-N-[(2S)-2-hydroxy-3-(4-morpholinyl)propyl]-2,4-dimethyl-1H-pyrrol-3-carboxamid [German] [ACD/IUPAC Name]
5-[(E)-(5-Fluoro-2-oxo-1,2-dihydro-3H-indol-3-ylidene)methyl]-N-[(2S)-2-hydroxy-3-(4-morpholinyl)propyl]-2,4-dimethyl-1H-pyrrole-3-carboxamide [ACD/IUPAC Name]
5-[(E)-(5-Fluoro-2-oxo-1,2-dihydro-3H-indol-3-ylidène)méthyl]-N-[(2S)-2-hydroxy-3-(4-morpholinyl)propyl]-2,4-diméthyl-1H-pyrrole-3-carboxamide [French] [ACD/IUPAC Name]
627908-92-3 [RN]
SU 14813
452105-23-6 [RN]
SU14813
SU-14813
  • Experimental Physico-chemical Properties
  • Miscellaneous

    • Bio Activity:

      SU14813 is an oral, multitargeted tyrosine kinase inhibitor (TKI) targeting vascular endothelial growth factor receptors (VEGFR), platelet-derived growth factor receptors (PDGFR), Kit, and fms-like ty rosine kinase 3 (FLT-3). MedChem Express

Predicted data is generated using the ACD/Labs Percepta Platform - PhysChem Module, version: 14.00

Density: 1.3±0.1 g/cm3
Boiling Point: 685.6±55.0 °C at 760 mmHg
Vapour Pressure: 0.0±2.2 mmHg at 25°C
Enthalpy of Vaporization: 105.6±3.0 kJ/mol
Flash Point: 368.5±31.5 °C
Index of Refraction: 1.635
Molar Refractivity: 118.0±0.3 cm3
#H bond acceptors: 8
#H bond donors: 4
#Freely Rotating Bonds: 6
#Rule of 5 Violations: 0
ACD/LogP: 2.01
ACD/LogD (pH 5.5): 0.58
ACD/BCF (pH 5.5): 1.00
ACD/KOC (pH 5.5): 18.47
ACD/LogD (pH 7.4): 1.47
ACD/BCF (pH 7.4): 7.55
ACD/KOC (pH 7.4): 144.10
Polar Surface Area: 107 Å2
Polarizability: 46.8±0.5 10-24cm3
Surface Tension: 58.9±3.0 dyne/cm
Molar Volume: 329.7±3.0 cm3

Click to predict properties on the Chemicalize site


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