ChemSpider 2D Image | CHZ868 | C22H19F2N5O2

CHZ868

  • Molecular FormulaC22H19F2N5O2
  • Average mass423.415 Da
  • Monoisotopic mass423.150696 Da
  • ChemSpider ID57876249

More details:

Validated by Experts, Validated by Users, Non-Validated, Removed by Users

1895895-38-1 [RN]
Acetamide, N-[4-[[2-[(2,4-difluorophenyl)amino]-1,4-dimethyl-1H-benzimidazol-5-yl]oxy]-2-pyridinyl]- [ACD/Index Name]
CHZ868
N-[4-({2-[(2,4-difluorophenyl)amino]-1,4-dimethyl-1,3-benzodiazol-5-yl}oxy)pyridin-2-yl]acetamide
N-[4-({2-[(2,4-difluorophenyl)amino]-1,4-dimethyl-1H-1,3-benzodiazol-5-yl}oxy)pyridin-2-yl]acetamide
N-[4-({2-[(2,4-Difluorophenyl)amino]-1,4-dimethyl-1H-benzimidazol-5-yl}oxy)-2-pyridinyl]acetamide [ACD/IUPAC Name]
N-[4-({2-[(2,4-Difluorophényl)amino]-1,4-diméthyl-1H-benzimidazol-5-yl}oxy)-2-pyridinyl]acétamide [French] [ACD/IUPAC Name]
N-[4-({2-[(2,4-Difluorphenyl)amino]-1,4-dimethyl-1H-benzimidazol-5-yl}oxy)-2-pyridinyl]acetamid [German] [ACD/IUPAC Name]
CHZ 868
CHZ-868
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  • Miscellaneous

    • Chemical Class:

      A memger of the class of benzimidazoles that is benzimidazole that is substituted by methyl groups at positions 1 and 4, by a 2,4-difluoroanilino group at position 2, and by a (2-acetamidopyridin-4-yl )oxy group at position 5. It is a type II JAK2 inhibitor with antineoplastic activity. ChEBI CHEBI:90828

Predicted data is generated using the ACD/Labs Percepta Platform - PhysChem Module, version: 14.00

Density: 1.4±0.1 g/cm3
Boiling Point:
Vapour Pressure:
Enthalpy of Vaporization:
Flash Point:
Index of Refraction: 1.640
Molar Refractivity: 111.3±0.5 cm3
#H bond acceptors: 7
#H bond donors: 2
#Freely Rotating Bonds: 5
#Rule of 5 Violations: 1
ACD/LogP: 5.11
ACD/LogD (pH 5.5): 4.34
ACD/BCF (pH 5.5): 1047.56
ACD/KOC (pH 5.5): 4415.04
ACD/LogD (pH 7.4): 4.54
ACD/BCF (pH 7.4): 1670.30
ACD/KOC (pH 7.4): 7039.64
Polar Surface Area: 81 Å2
Polarizability: 44.1±0.5 10-24cm3
Surface Tension: 45.0±7.0 dyne/cm
Molar Volume: 309.0±7.0 cm3

Click to predict properties on the Chemicalize site


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