ChemSpider 2D Image | PNU-282,987 | C14H18Cl2N2O

PNU-282,987

  • Molecular FormulaC14H18Cl2N2O
  • Average mass301.211 Da
  • Monoisotopic mass300.079620 Da
  • ChemSpider ID9418572

  • defined stereocentres - 1 of 1 defined stereocentres

More details:

Validated by Experts, Validated by Users, Non-Validated, Removed by Users

123464-89-1 [RN]
810P1694K2
Benzamide, N-(3R)-1-azabicyclo[2.2.2]oct-3-yl-4-chloro-, hydrochloride (1:1)
Benzamide, N-[(3R)-1-azabicyclo[2.2.2]oct-3-yl]-4-chloro-, hydrochloride (1:1) [ACD/Index Name]
N-[(3R)-1-Azabicyclo[2.2.2]oct-3-yl]-4-chlorbenzamidhydrochlorid (1:1) [German] [ACD/IUPAC Name]
N-[(3R)-1-Azabicyclo[2.2.2]oct-3-yl]-4-chlorobenzamide hydrochloride (1:1) [ACD/IUPAC Name]
N-[(3R)-1-Azabicyclo[2.2.2]oct-3-yl]-4-chlorobenzamide, chlorhydrate (1:1) [French] [ACD/IUPAC Name]
N-[(3R)-1-AZABICYCLO[2.2.2]OCTAN-3-YL]-4-CHLOROBENZAMIDE HYDROCHLORIDE
PNU-282,987 [Wiki]
(R)-4-Chloro-N-(quinuclidin-3-yl)benzamide hydrochloride
More...
  • Experimental Physico-chemical Properties
  • Miscellaneous

    • Bio Activity:

      Membrane Tranporter/Ion Channel MedChem Express HY-12560A
      Membrane Tranporter/Ion Channel; Neuronal Signaling; MedChem Express HY-12560A
      nAChR MedChem Express HY-12560A
      PNU-282987 is a selective ?7 nicotinic acetylcholine receptor(?7 nAChR) agonist with Ki of 26 nM; no affinity for ?1?1?? and ?3?4 nAChRs (IC50 ? 60 ?M).; IC50 value: 26 nM(Ki) [1]; Target: ?7 nAChR agonist; in vitro: Treatment with PNU-282987 resulted in an attenuation of neuroinflammation in the MPTP-lesioned SN. MedChem Express HY-12560A

Predicted data is generated using the ACD/Labs Percepta Platform - PhysChem Module, version: 14.00

No predicted properties have been calculated for this compound.

Click to predict properties on the Chemicalize site


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