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Search term: NEXGBSJERNQRSV-UHFFFAOYSA-N (Found by InChIKey (full match))
ChemSpider 2D Image | SBI-0206965 | C21H21BrN4O5

SBI-0206965

  • Molecular FormulaC21H21BrN4O5
  • Average mass489.319 Da
  • Monoisotopic mass488.069519 Da
  • ChemSpider ID35519223

More details:

Validated by Experts, Validated by Users, Non-Validated, Removed by Users

1884220-36-3 [RN]
2-((5-bromo-2-((3,4,5-trimethoxyphenyl)amino)pyrimidin-4-yl)oxy)-N-methylbenzamide
2-({5-Brom-2-[(3,4,5-trimethoxyphenyl)amino]-4-pyrimidinyl}oxy)-N-methylbenzamid [German] [ACD/IUPAC Name]
2-({5-Bromo-2-[(3,4,5-trimethoxyphenyl)amino]-4-pyrimidinyl}oxy)-N-methylbenzamide [ACD/IUPAC Name]
2-({5-Bromo-2-[(3,4,5-triméthoxyphényl)amino]-4-pyrimidinyl}oxy)-N-méthylbenzamide [French] [ACD/IUPAC Name]
2-({5-bromo-2-[(3,4,5-trimethoxyphenyl)amino]pyrimidin-4-yl}oxy)-N-methylbenzamide
Benzamide, 2-[[5-bromo-2-[(3,4,5-trimethoxyphenyl)amino]-4-pyrimidinyl]oxy]-N-methyl- [ACD/Index Name]
SBI-0206965
1538604-68-0 [RN]
2-[[5-bromo-2-[(3,4,5-trimethoxyphenyl)amino]-4-pyrimidinyl]oxy]-N-methyl-benzamide
More...
  • Experimental Physico-chemical Properties
  • Miscellaneous

    • Bio Activity:

      Others MedChem Express HY-16966
      SBI-0206965 is a potent, selective and cell permeable autophagy kinase ULK1 inhibitor with IC50 of 108 nM for ULK1 kinase activity and 711 nM for the highly related kinase ULK2 .; IC50 value: 108nM/711 nM; Target: ULK1/ ULK2; in vitro: SBI-0206965 has very high selectivity, only inhibits 10 out of 456 kinases >95% when tested at 10 ?M. MedChem Express HY-16966
      ULK MedChem Express HY-16966

Predicted data is generated using the ACD/Labs Percepta Platform - PhysChem Module, version: 14.00

Density: 1.4±0.1 g/cm3
Boiling Point:
Vapour Pressure:
Enthalpy of Vaporization:
Flash Point:
Index of Refraction: 1.619
Molar Refractivity: 119.6±0.3 cm3
#H bond acceptors: 9
#H bond donors: 2
#Freely Rotating Bonds: 8
#Rule of 5 Violations: 0
ACD/LogP: 3.26
ACD/LogD (pH 5.5): 2.92
ACD/BCF (pH 5.5): 98.07
ACD/KOC (pH 5.5): 927.14
ACD/LogD (pH 7.4): 2.92
ACD/BCF (pH 7.4): 98.09
ACD/KOC (pH 7.4): 927.31
Polar Surface Area: 104 Å2
Polarizability: 47.4±0.5 10-24cm3
Surface Tension: 51.5±3.0 dyne/cm
Molar Volume: 341.0±3.0 cm3

Click to predict properties on the Chemicalize site


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