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Search term: RPBMXJHQYJLPDN-UHFFFAOYSA-N (Found by InChIKey (full match))
ChemSpider 2D Image | TP-472 | C20H19N3O2

TP-472

  • Molecular FormulaC20H19N3O2
  • Average mass333.384 Da
  • Monoisotopic mass333.147736 Da
  • ChemSpider ID58830970

More details:

Validated by Experts, Validated by Users, Non-Validated, Removed by Users

2079895-62-6 [RN]
3-(6-Acetylpyrrolo[1,2-a]pyrimidin-8-yl)-N-cyclopropyl-4-methylbenzamid [German] [ACD/IUPAC Name]
3-(6-Acetylpyrrolo[1,2-a]pyrimidin-8-yl)-N-cyclopropyl-4-methylbenzamide [ACD/IUPAC Name]
3-(6-Acetyl-pyrrolo[1,2-a]pyrimidin-8-yl)-N-cyclopropyl-4-methyl-benzamide
3-(6-Acétylpyrrolo[1,2-a]pyrimidin-8-yl)-N-cyclopropyl-4-méthylbenzamide [French] [ACD/IUPAC Name]
Benzamide, 3-(6-acetylpyrrolo[1,2-a]pyrimidin-8-yl)-N-cyclopropyl-4-methyl- [ACD/Index Name]
TP-472
3-(6-acetylpyrrolo[1,2-a]pyrimidin-8-yl)-N-cyclopropyl-4-methyl-benzamide
MFCD30536375
TP 472
  • Experimental Physico-chemical Properties
  • Miscellaneous

    • Safety:

      This probe is supplied in conjunction with the Structural Genomics Consortium. For further characterization details, please visit the TP 472 probe summary on the SGC website. Tocris Bioscience 6000

    • Bio Activity:

      Bromodomains Tocris Bioscience 6000
      Epigenetics Tocris Bioscience 6000
      Potent BRD9/7 inhibitor Tocris Bioscience 6000
      Potent BRD9/7 inhibitor (Kd values are 33 and 340 nM, respectively) Exhibits >30-fold selectivity for BRD9 over other bromodomains except BRD7. Cell permeable and active in vivo. Negative Control also available. Tocris Bioscience 6000
      Potent BRD9/7 inhibitor (Kd values are 33 and 340 nM, respectively) Exhibits >30-fold selectivity for BRD9 over other bromodomains except BRD7. Cell permeable and active in vivo. Negative control TP 472N (Cat. No. 5999) available. Tocris Bioscience 6000

Predicted data is generated using the ACD/Labs Percepta Platform - PhysChem Module, version: 14.00

Density: 1.3±0.1 g/cm3
Boiling Point:
Vapour Pressure:
Enthalpy of Vaporization:
Flash Point:
Index of Refraction: 1.681
Molar Refractivity: 95.9±0.5 cm3
#H bond acceptors: 5
#H bond donors: 1
#Freely Rotating Bonds: 4
#Rule of 5 Violations: 0
ACD/LogP: 1.25
ACD/LogD (pH 5.5): 2.24
ACD/BCF (pH 5.5): 29.68
ACD/KOC (pH 5.5): 394.11
ACD/LogD (pH 7.4): 2.24
ACD/BCF (pH 7.4): 29.68
ACD/KOC (pH 7.4): 394.11
Polar Surface Area: 63 Å2
Polarizability: 38.0±0.5 10-24cm3
Surface Tension: 51.0±7.0 dyne/cm
Molar Volume: 253.5±7.0 cm3

Click to predict properties on the Chemicalize site


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