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- Dual-channel surface plasmon resonance monitoring of intracellular levels of the p53-MDM2 complex and caspase-3 induced by MDM2 antagonist Nutlin-3. Ling Wu, Yuqing Hu, Yuhan He, Yonghong Xia, Hanwen Lu, Zhong Cao, Xinyao Yi, Jianxiu Wang
, Analyst
, 2019
, 144
, 3959
- Solid-state nanopore analysis on conformation change of p53TAD–MDM2 fusion protein induced by protein–protein interaction. Hongsik Chae, Dong-Kyu Kwak, Mi-Kyung Lee, Seung-Wook Chi, Ki-Bum Kim
, Nanoscale
, 2018
, 10
, 17227
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Catalytic, enantioselective synthesis of stilbenecis-diamines: A concise preparation of (−)-Nutlin-3, a potent p53/MDM2 inhibitor. Tyler A. Davis, Jeffrey N. Johnston
, Chem. Sci.
, 2011
, 2
, 1076
- Environment-sensitive turn-on fluorescent probes for p53–MDM2 protein–protein interaction. Tingting Liu, Yan Jiang, Zhenzhen Liu, Jin Li, Kun Fang, Chunlin Zhuang, Lupei Du, Hao Fang, Chunquan Sheng, Minyong Li
, Med. Chem. Commun.
, 2017
, 8
, 1668
- Asymmetric organocatalysis: an enabling technology for medicinal chemistry. Bo Han, Xiang-Hong He, Yan-Qing Liu, Gu He, Cheng Peng, Jun-Long Li
, Chem. Soc. Rev.
, 2021
, 50
, 1522
- Single-molecule analysis of interaction between p53TAD and MDM2 using aerolysin nanopores. Sohee Oh, Mi-Kyung Lee, Seung-Wook Chi
, Chem. Sci.
, 2021
, 12
, 5883
- Real-time surface plasmon resonance monitoring of site-specific phosphorylation of p53 protein and its interaction with MDM2 protein. Ling Wu, Yuhan He, Yuqing Hu, Hanwen Lu, Zhong Cao, Xinyao Yi, Jianxiu Wang
, Analyst
, 2019
, 144
, 6033
- Induction of apoptosis in MDA-MB-231 breast cancer cells by a PARP1-targeting PROTAC small molecule. Qiuye Zhao, Tianlong Lan, Shang Su, Yu Rao
, Chem. Commun.
, 2019
, 55
, 369
- Dual mode of action of phenyl-pyrazole-phenyl (6-5-6 system)-based PPI inhibitors: alpha-helix backbone versus alpha-helix binding epitope. Natalya I. Vasilevich, Ilya I. Afanasyev, Eugene A. Rastorguev, Dmitry V. Genis, Valery S. Kochubey
, Med. Chem. Commun.
, 2013
, 4
, 1597
- Rapid identification of dual p53-MDM2/MDMX interaction inhibitors through virtual screening and hit-based substructure search. Si Chen, Xiang Li, Weirong Yuan, Yan Zou, Zhongwu Guo, Yifeng Chai, Wuyuan Lu
, RSC Adv.
, 2017
, 7
, 9989