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Epoxide formation in the enzymic conversion of [4-2 H]exomethylene cephalosporin C by deacetoxy-/deacetylcephalosporin C synthase . Jack E. Baldwin, Robert M. Adlington, Nicholas P. Crouch, Inês A. C. Pereira
, J. Chem. Soc., Chem. Commun.
, 1992
, 1448
The role of molecular oxygen in cephalosporin C biosynthesis . Jack E. Baldwin, Robert M. Adlington, Christopher J. Schofield, Nicholas P. Crouch, Hong-Hoi Ting
, J. Chem. Soc., Chem. Commun.
, 1987
, 1556
Water exchange of intermediates in a non-haem iron, α-ketoglutarate dioxygenase, deacetoxy-/deacetylcephalosporin C synthase . Jack E. Baldwin, Robert M. Adlington, Nicholas P. Crouch, Inês A. C. Pereira, Robin T. Aplin, Carol Robinson
, J. Chem. Soc., Chem. Commun.
, 1993
, 105
The enzymes of β-lactam biosynthesis . Refaat B. Hamed, J. Ruben Gomez-Castellanos, Luc Henry, Christian Ducho, Michael A. McDonough, Christopher J. Schofield
, Nat. Prod. Rep.
, 2013
, 30
, 21
Cephalosporin C biosynthesis; stereochemistry of the incorporation of D,L,D -α-aminodipoyl-cysteinyl-(3S )-[2-2 H,4-13 C]valine into β-lactam compounds . Jack E. Baldwin, Robert M. Adlington, Nicholas P. Crouch, Nicholas J. Turner, Christopher J. Schofield
, J. Chem. Soc., Chem. Commun.
, 1989
, 1141
Studies on the mechanism of deacetoxy–deacetylcephalosporin C synthase using cyclopropyl substituted cephalosporin probes . Jack E. Baldwin, Robert M. Adlington, Nicholas P. Crouch, John W. Keeping, Simon W. Leppard, Janos Pitlik, Christopher J. Schofield, Wendy J. Sobey, Mark E. Wood
, J. Chem. Soc., Chem. Commun.
, 1991
, 768
The iron(II ) and 2-oxoacid-dependent dioxygenases and their role in metabolism . Andy G. Prescott, Matthew D. Lloyd
, Nat. Prod. Rep.
, 2000
, 17
, 367
Roles of 2-oxoglutarate oxygenases and isopenicillin N synthase in β-lactam biosynthesis . Patrick Rabe, Jos J. A. G. Kamps, Christopher J. Schofield, Christopher T. Lohans
, Nat. Prod. Rep.
, 2018
, 35
, 735
Stereochemical investigation of the α-ketoglutarate-dependent 3′-hydroxylation in cephalosporin biosynthesis . Craig A. Townsend, Ellen B. Barrabee
, J. Chem. Soc., Chem. Commun.
, 1984
, 1586
Stepwise hydrogen removal in the enzymic ring expansion of penicillin N to deacetoxycephalosporin C . Jack E. Baldwin, Robert M. Adlington, Robin T. Aplin, Nicholas P. Crouch, Christopher J. Schofield, Hong-Hoi Ting
, J. Chem. Soc., Chem. Commun.
, 1987
, 1654