The aim of the present study is to evaluate the quantitative contribution of passive permeability to P-glycoprotein-mediated (P-gp-mediated) efflux and the functional activity of P-gp in determining intestinal absorption of drugs, and demonstrate the relationship between efflux parameters and intestinal permeability. The associated datasets are available on QSAR world at: http://www.qsarworld.com/qsar-datasets-varma.php
Guan Longfei, Yang Hongbin, Cai Yingchun, Sun Lixia, Di Peiwen, Li Weihua, Liu Guixia, Tang Yun.
ADMET-score – a comprehensive scoring function for evaluation of chemical drug-likeness, MedChemComm, 2019