Results
1 -
7 of
7
(Click
here to explore results)
- LY2874455 potently inhibits FGFR gatekeeper mutants and overcomes mutation-based resistance. Daichao Wu, Ming Guo, Xiaoli Min, Shuyan Dai, Meixiang Li, Sijie Tan, Guoqing Li, Xiaojuan Chen, Yao Ma, Jun Li, Longying Jiang, Lingzhi Qu, Zhan Zhou, Zhuchu Chen, Lin Chen, Guangyu Xu, Yongheng Chen
, Chem. Commun.
, 2018
, 54
, 12089
- The application of the MM/GBSA method in the binding pose prediction of FGFR inhibitors. Yu Chen, Yongxiang Zheng, Pedro Fong, Shengjun Mao, Qiantao Wang
, Phys. Chem. Chem. Phys.
, 2020
, 22
, 9656
- Characterization of FGF401 as a reversible covalent inhibitor of fibroblast growth factor receptor 4. Zhan Zhou, Xiaojuan Chen, Ying Fu, Ye Zhang, Shuyan Dai, Jun Li, Lin Chen, Guangyu Xu, Zhuchu Chen, Yongheng Chen
, Chem. Commun.
, 2019
, 55
, 5890
- Synthesis and biological evaluation of indazole derivatives as anti-cancer agents. Wei Wei, Zhihao Liu, Xiuli Wu, Cailing Gan, Xingping Su, Hongyao Liu, Hanyun Que, Qianyu Zhang, Qiang Xue, Lin Yue, Luoting Yu, Tinghong Ye
, RSC Adv.
, 2021
, 11
, 15675
- The irony of chirality – unveiling the distinct mechanistic binding and activities of 1-(3-(4-amino-5-(7-methoxy-5-methylbenzo[b]thiophen-2-yl)-7H-pyrrolo[2,3-d]pyrimidin-7-yl)pyrrolidin-1-yl)prop-2-en-1-one enantiomers as irreversible covalent FGFR4 inhibitors. Farideh Badichi Akher, Abdolkarim Farrokhzadeh, Fisayo A. Olotu, Clement Agoni, Mahmoud E. S. Soliman
, Org. Biomol. Chem.
, 2019
, 17
, 1176
- Design, synthesis and biological evaluation of novel FGFR inhibitors bearing an indazole scaffold. Jian Liu, Xia Peng, Yang Dai, Wei Zhang, Sumei Ren, Jing Ai, Meiyu Geng, Yingxia Li
, Org. Biomol. Chem.
, 2015
, 13
, 7643
- Design, synthesis and biological evaluation of 1H-pyrrolo[2,3-b]pyridine derivatives as potent fibroblast growth factor receptor inhibitors. Xingping Su, Zhihao Liu, Lin Yue, Xiuli Wu, Wei Wei, Hanyun Que, Tinghong Ye, Yi Luo, Yiwen Zhang
, RSC Adv.
, 2021
, 11
, 20651