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- Actin filaments play a primary role for structural integrity and viscoelastic response in cells. Alperen N. Ketene, Paul C. Roberts, Amanda A. Shea, Eva M. Schmelz, Masoud Agah
, Integr. Biol.
, 2012
, 4
, 540
- Potent and selective HDAC6 inhibitory activity of N-(4-hydroxycarbamoylbenzyl)-1,2,4,9-tetrahydro-3-thia-9-azafluorenes as novel sulfur analogues of Tubastatin A. Rob De Vreese, Tom Verhaeghe, Tom Desmet, Matthias D'hooghe
, Chem. Commun.
, 2013
, 49
, 3775
- Synthesis and SAR assessment of novel Tubathian analogs in the pursuit of potent and selective HDAC6 inhibitors. Rob De Vreese, Yves Depetter, Tom Verhaeghe, Tom Desmet, Veronick Benoy, Wanda Haeck, Ludo Van Den Bosch, Matthias D′hooghe
, Org. Biomol. Chem.
, 2016
, 14
, 2537
- A highly HDAC6-selective inhibitor acts as a fluorescent probe. Yi-Hsun Ho, Kuang-Jui Wang, Pei-Yun Hung, Yi-Sheng Cheng, Jia-Rong Liu, Sheang-Tze Fung, Pi-Hui Liang, Ji-Wang Chern, Chao-Wu Yu
, Org. Biomol. Chem.
, 2018
, 16
, 7820
- Synthesis of benzothiophene-based hydroxamic acids as potent and selective HDAC6 inhibitors. Rob De Vreese, Nicholas Van Steen, Tom Verhaeghe, Tom Desmet, Nadia Bougarne, Karolien De Bosscher, Veronick Benoy, Wanda Haeck, Ludo Van Den Bosch, Matthias D'hooghe
, Chem. Commun.
, 2015
, 51
, 9868
- Rational design and diversity-oriented synthesis of peptoid-based selective HDAC6 inhibitors. D. Diedrich, A. Hamacher, C. G. W. Gertzen, L. A. Alves Avelar, G. J. Reiss, T. Kurz, H. Gohlke, M. U. Kassack, F. K. Hansen
, Chem. Commun.
, 2016
, 52
, 3219
- Shifting the paradigm in treating multi-factorial diseases: polypharmacological co-inhibitors of HDAC6. Alexandria M. Chan, Steven Fletcher
, RSC Med. Chem.
, 2021
, 12
, 178
- Borinostats: solid-phase synthesis of carborane-capped histone deacetylase inhibitors with a tailor-made selectivity profile. Christoph Selg, Andrea Schöler, Julian Schliehe-Diecks, Maria Hanl, Laura Sinatra, Arndt Borkhardt, Menyhárt B. Sárosi, Sanil Bhatia, Evamarie Hey-Hawkins, Finn K. Hansen
, Chem. Sci.
, 2021
, 12
, 11873
- Assessment of the trifluoromethyl ketone functionality as an alternative zinc-binding group for selective HDAC6 inhibition. Yves Depetter, Silke Geurs, Flore Vanden Bussche, Rob De Vreese, Jorick Franceus, Tom Desmet, Olivier De Wever, Matthias D'hooghe
, Med. Chem. Commun.
, 2018
, 9
, 1011
- Next-generation of selective histone deacetylase inhibitors. Feifei Yang, Na Zhao, Di Ge, Yihua Chen
, RSC Adv.
, 2019
, 9
, 19571