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- An investigation of the metabolic activity, isozyme contribution, species differences and potential drug–drug interactions of PI-103, and the identification of efflux transporters for PI-103-O-glucuronide in HeLa1A9 cells. Li Gao, Zifei Qin, Beibei Zhang, Zhao Yin, Xiaojian Zhang, Jing Yang
, RSC Adv.
, 2020
, 10
, 9610
- Biomimetic tumor-induced angiogenesis and anti-angiogenic therapy in a microfluidic model. Lilu Liu, Zhaorong Xie, Wenyuan Zhang, Shimeng Fang, Jing Kong, Dong Jin, Jiao Li, Xiaojie Li, Xuesong Yang, Yong Luo, Bingcheng Lin, Tingjiao Liu
, RSC Adv.
, 2016
, 6
, 35248
- Inhibitors of phosphoinositide-3-kinase: a structure-based approach to understanding potency and selectivity. Teather J. Sundstrom, Amy C. Anderson, Dennis L. Wright
, Org. Biomol. Chem.
, 2009
, 7
, 840
- Discovery of a novel phosphoinositide 3-kinase gamma (PI3Kγ) inhibitor against hematologic malignancies and theoretical studies on its PI3Kγ-specific binding mechanisms. Jingyu Zhu, Ke Ke, Lei Xu, Jian Jin
, RSC Adv.
, 2019
, 9
, 20207
- Multi-pathway cellular analysis of compound selectivity. Michael K. Hancock, Connie S. Lebakken, Jun Wang, Kun Bi
, Mol. BioSyst.
, 2010
, 6
, 1834
- One-pot two-step catalytic synthesis of 6-amino-2-pyridone-3,5-dicarbonitriles enabling anti-cancer bioactivity. Lynden G. Nicely, Ruturajsinh M. Vala, Dipti B. Upadhyay, Joaquina Nogales, Celestine Chi, Sourav Banerjee, Hitendra M. Patel
, RSC Adv.
, 2022
, 12
, 23889
- Conformationally restricted quinazolone derivatives as PI3Kδ-selective inhibitors: the design, synthesis and biological evaluation. Xiaodong Ma, Fang Fang, Qiangqiang Tao, Li Shen, Guochen Zhong, Tao Qiao, Xiaoqing Lv, Jiaming Li
, Med. Chem. Commun.
, 2019
, 10
, 413
- Zinc-dependent effects of small molecules on the insulin-sensitive transcription factor FOXO1a and gluconeogenic genes. Amy R. Cameron, Siji Anil, Emma Sutherland, Jean Harthill, Graham Rena
, Metallomics
, 2010
, 2
, 195
- Research and development of N,N′-diarylureas as anti-tumor agents. Xueyan Sun, Zhizhong Xie, Xiaoyong Lei, Sheng Huang, Guotao Tang, Zhe Wang
, RSC Med. Chem.
, 2023
, 14
, 1209
- Novel quinoline-derived mTOR inhibitors with remarkable enzymatic and cellular activities: design, synthesis and biological evaluation. Xiao-Dong Ma, Ni Qiu, Bo Yang, Qiao-Jun He, Yong-Zhou Hu
, Med. Chem. Commun.
, 2016
, 7
, 297