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- Concise synthesis and biological activity evaluation of novel pyrazinyl–aryl urea derivatives against several cancer cell lines, which can especially induce T24 apoptotic and necroptotic cell death. Jia-Nian Chen, Chu-Ting Chen, Yue-Zhen He, Tai-Sheng Qin, Li Cheng, Ye-Xiang Sun, Kang-Jian Yang, Qi Chen, Chao Yang, Ying Wei
, RSC Med. Chem.
, 2022
, 13
, 280
- New pyrazolylindolin-2-one based coumarin derivatives as anti-melanoma agents: design, synthesis, dual BRAFV600E/VEGFR-2 inhibition, and computational studies. Ahmed Sabt, Mohammed A. Khedr, Wagdy M. Eldehna, Abdelsamed I. Elshamy, Mohamed F. Abdelhameed, Rasha M. Allam, Rasha Z. Batran
, RSC Adv.
, 2024
, 14
, 5907
- The synthesis of Bcr-Abl inhibiting anticancer pharmaceutical agents imatinib, nilotinib and dasatinib. Benjamin J. Deadman, Mark D. Hopkin, Ian R. Baxendale, Steven V. Ley
, Org. Biomol. Chem.
, 2013
, 11
, 1766
- Regorafenib analogues and their ferrocenic counterparts: synthesis and biological evaluation. Myron Wilde, Danielle Arzur, Blandine Baratte, Dorian Lefebvre, Thomas Robert, Thierry Roisnel, Catherine Le Jossic-Corcos, Stéphane Bach, Laurent Corcos, William Erb
, New J. Chem.
, 2020
, 44
, 19723
- Characterization of degradation products of regorafenib by LC-QTOF-MS and NMR spectroscopy: investigation of rearrangement and odd-electron ion formation during collision-induced dissociations under ESI-MS/MS. Shandilya Mahamuni Baira, Gannoju Srinivasulu, Rakesh Nimbalkar, Prabha Garg, R. Srinivas, M. V. N. Kumar Talluri
, New J. Chem.
, 2017
, 41
, 12091
- Cocrystals of regorafenib with dicarboxylic acids: synthesis, characterization and property evaluation. Jun-Long Jia, Xia-Lin Dai, Hao-Jie Che, Meng-Ting Li, Xiao-Mei Zhuang, Tong-Bu Lu, Jia-Mei Chen
, CrystEngComm
, 2021
, 23
, 653
- Dual-targeting biomimetic delivery for anti-glioma activity via remodeling the tumor microenvironment and directing macrophage-mediated immunotherapy. Pengfei Zhao, Yonghui Wang, Xuejia Kang, Aihua Wu, Weimin Yin, Yisi Tang, Jinyu Wang, Meng Zhang, Yifei Duan, Yongzhuo Huang
, Chem. Sci.
, 2018
, 9
, 2674
- New methods to assess 6-thiopurine toxicity and expanding its therapeutic application to pancreatic cancer via small molecule potentiators. Chamitha Weeramange, Ashabha Lansakara, Johnathan Dallman, Thi Nguyen, Wasundara Hulangamuwa, Ryan J. Rafferty
, Med. Chem. Commun.
, 2019
, 10
, 717
- Direct monitoring of the conformational equilibria of the activation loop in the mitogen-activated protein kinase p38α. Patrick Roser, Jörn Weisner, Jeffrey R. Simard, Daniel Rauh, Malte Drescher
, Chem. Commun.
, 2018
, 54
, 12057
- Efforts in redesigning the antileukemic drug 6-thiopurine: decreasing toxic side effects while maintaining efficacy. Arnaldo X. Torres Hernandez, Chamitha J. Weeramange, Prathibha Desman, Anthony Fatino, Olivia Haney, Ryan J. Rafferty
, Med. Chem. Commun.
, 2019
, 10
, 169