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3The Domain Structure of Poly(ADP-Ribose) Synthetase and Its Role in Accurate Transcription Initiation, ADP-Ribosylation of Proteins Antiangiogenic and growth inhibitory effects of synthetic novel 1, 5-diphenyl-1,4 pentadiene-3-one-3-yl-ethanone pyridine curcumin analogues on Ehrlich ascites tumor in vivo, Medicinal Chemistry Research