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15Prophylactic Effect of Irsogladine Maleate Against Indomethacin-Induced Small Intestinal Lesions in Rats, Digestive Diseases and Sciences A new synthetic matrix metalloproteinase inhibitor modulates both angiogenesis and urokinase type plasminogen activator activity, Angiogenesis Complete disappearance of metastatic abdominal tumors from gastric cancer after treatment with irsogladine maleate, Journal of Cancer Research and Clinical Oncology Angiogenesis as a new target for cancer treatment, Cancer Chemotherapy and Pharmacology The time course of gap-junctional protein connexin 32 expression in the pancreas after the induction of acute pancreatitis by caerulein in rats, Journal of Gastroenterology Up-regulation of Urokinase-type Plasminogen Activator and its Receptor Correlates with Enhanced Invasion Activity of Human Glioma Cells Mediated by Transforming Growth Factor-?? or Basic Fibroblast Growth Factor, Journal of Neuro-Oncology Preventive effect of irsogladine or omeprazole on non-steroidal anti-inflammatory drug-induced esophagitis, peptic ulcers, and small intestinal lesions in humans, a prospective randomized controlled study, BMC Gastroenterology